AFfirm™ ARHGAP42 Mouse Monoclonal Antibody - #BF8862

Product: ARHGAP42 Mouse Monoclonal Antibody
Catalog: BF8862
Description: Mouse monoclonal antibody to ARHGAP42
Application: WB
Reactivity: Human
Prediction: Human, Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
Mol.Wt.: 100~130kDa; 99kD(Calculated).
Uniprot: A6NI28

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 100ul $175 350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Mouse
Application:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Monoclonal [AFfirm8862]
Specificity:
ARHGAP42 Mouse Monoclonal Antibody detects endogenous levels of total ARHGAP42.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

ARHGAP42; FLJ32810; GRAF3; RHG42_HUMAN; Rho GTPase-activating protein 10-like; Rho GTPase-activating protein 42; Rho-type GTPase-activating protein 42;

Immunogens

Immunogen:
Uniprot:

A6NI28(RHG42_HUMAN) >>Visit HPA database.

Gene(ID):
ARHGAP42(143872)
Expression:
A6NI28 RHG42_HUMAN:

Highly and selectively expressed in smooth muscle cells.

Sequence:
MGLPTLEFSDSYLDSPDFRERLQCHEIELERTNKFIKELIKDGSLLIGALRNLSMAVQKFSQSLQDFQFECIGDAETDDEISIAQSLKEFARLLIAVEEERRRLIQNANDVLIAPLEKFRKEQIGAAKDGKKKFDKESEKYYSILEKHLNLSAKKKESHLQEADTQIDREHQNFYEASLEYVFKIQEVQEKKKFEFVEPLLSFLQGLFTFYHEGYELAQEFAPYKQQLQFNLQNTRNNFESTRQEVERLMQRMKSANQDYRPPSQWTMEGYLYVQEKRPLGFTWIKHYCTYDKGSKTFTMSVSEMKSSGKMNGLVTSSPEMFKLKSCIRRKTDSIDKRFCFDIEVVERHGIITLQAFSEANRKLWLEAMDGKEPIYTLPAIISKKEEMYLNEAGFNFVRKCIQAVETRGITILGLYRIGGVNSKVQKLMNTTFSPKSPPDIDIDIELWDNKTITSGLKNYLRCLAEPLMTYKLHKDFIIAVKSDDQNYRVEAVHALVHKLPEKNREMLDILIKHLVKVSLHSQQNLMTVSNLGVIFGPTLMRAQEETVAAMMNIKFQNIVVEILIEHYEKIFHTAPDPSIPLPQPQSRSGSRRTRAICLSTGSRKPRGRYTPCLAEPDSDSYSSSPDSTPMGSIESLSSHSSEQNSTTKSASCQPREKSGGIPWIATPSSSNGQKSLGLWTTSPESSSREDATKTDAESDCQSVASVTSPGDVSPPIDLVKKEPYGLSGLKRASASSLRSISAAEGNKSYSGSIQSLTSVGSKETPKASPNPDLPPKMCRRLRLDTASSNGYQRPGSVVAAKAQLFENVGSPKPVSSGRQAKAMYSCKAEHSHELSFPQGAIFSNVYPSVEPGWLKATYEGKTGLVPENYVVFL

PTMs - A6NI28 As Substrate

Site PTM Type Enzyme
T32 Phosphorylation
K128 Acetylation
K131 Acetylation
Y142 Phosphorylation
K154 Ubiquitination
T332 Phosphorylation
Y376 Phosphorylation
T377 Phosphorylation
K424 Ubiquitination
S587 Phosphorylation
S638 Phosphorylation
S641 Phosphorylation
S683 Phosphorylation
S728 Phosphorylation
K731 Methylation
S734 Phosphorylation
S740 Phosphorylation
S742 Phosphorylation
S749 Phosphorylation
S751 Phosphorylation
S753 Phosphorylation
S769 Phosphorylation
T786 Phosphorylation
S788 Phosphorylation
S789 Phosphorylation
Y792 Phosphorylation
S797 Phosphorylation
S811 Phosphorylation
T858 Phosphorylation
Y870 Phosphorylation

Research Backgrounds

Function:

May influence blood pressure by functioning as a GTPase-activating protein for RHOA in vascular smooth muscle.

Tissue Specificity:

Highly and selectively expressed in smooth muscle cells.

Restrictive clause

 

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