AFfirm™ Peroxiredoxin 5 Mouse Monoclonal Antibody - #BF8849

Product: Peroxiredoxin 5 Mouse Monoclonal Antibody
Catalog: BF8849
Description: Mouse monoclonal antibody to Peroxiredoxin 5
Application: WB
Reactivity: Human
Prediction: Mouse, Rat, Pig, Zebrafish, Bovine, Horse, Sheep, Xenopus
Mol.Wt.: 17 kDa; 22kD(Calculated).
Uniprot: P30044

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 100ul $140 280 In stock

Lead Time: Same day delivery

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Mouse
Application:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Monoclonal [AFfirm8849]
Specificity:
Peroxiredoxin 5 Mouse Monoclonal Antibody detects endogenous levels of total Peroxiredoxin 5.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

ACR1; Alu co repressor 1; Alu corepressor 1; Antioxidant enzyme B166; AOEB166; B166; epididymis secretory protein Li 55; HEL-S-55; Liver tissue 2D-page spot 71B; mitochondrial; Peroxiredoxin 5, mitochondrial; Peroxiredoxin V; Peroxiredoxin-5; Peroxisomal antioxidant enzyme; PLP; PMP20; PRDX 5; PRDX5; PRDX5_HUMAN; PRDX6; Prx-V; PRXV; SBBI10; Thioredoxin peroxidase PMP20; Thioredoxin reductase; TPx type VI;

Immunogens

Immunogen:
Uniprot:

P30044(PRDX5_HUMAN) >>Visit HPA database.

Gene(ID):
PRDX5(25824)
Expression:
P30044 PRDX5_HUMAN:

Widely expressed.

Sequence:
MGLAGVCALRRSAGYILVGGAGGQSAAAAARRYSEGEWASGGVRSFSRAAAAMAPIKVGDAIPAVEVFEGEPGNKVNLAELFKGKKGVLFGVPGAFTPGCSKTHLPGFVEQAEALKAKGVQVVACLSVNDAFVTGEWGRAHKAEGKVRLLADPTGAFGKETDLLLDDSLVSIFGNRRLKRFSMVVQDGIVKALNVEPDGTGLTCSLAPNIISQL

PTMs - P30044 As Substrate

Site PTM Type Enzyme
S34 Phosphorylation
K75 Ubiquitination
K83 Acetylation
K83 Ubiquitination
K86 Ubiquitination
T97 Phosphorylation
C100 S-Nitrosylation
S101 Phosphorylation
K102 Ubiquitination
K116 Ubiquitination
K118 Ubiquitination
K146 Ubiquitination
K159 Ubiquitination
S182 Phosphorylation

Research Backgrounds

Function:

Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.

Subcellular Location:

Mitochondrion.

Cytoplasm. Peroxisome matrix.
Note: Imported into peroxisomes via peroxisomal targeting signal 1 receptor PEX5.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Widely expressed.

Subunit Structure:

Monomer.

Family&Domains:

Belongs to the peroxiredoxin family. Prx5 subfamily.

Research Fields

· Cellular Processes > Transport and catabolism > Peroxisome.   (View pathway)

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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