Cyclophilin B Mouse Monoclonal Antibody - #BF8825

Product: Cyclophilin B Mouse Monoclonal Antibody
Catalog: BF8825
Description: Mouse monoclonal antibody to Cyclophilin B
Application: WB
Reactivity: Human
Prediction: Mouse, Rat, Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Chicken, Xenopus
Mol.Wt.: 24 kDa; 24kD(Calculated).
Uniprot: P23284

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 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Mouse
Application:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Monoclonal [AFfirm8825]
Specificity:
Cyclophilin B Mouse Monoclonal Antibody detects endogenous levels of total Cyclophilin B.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

AA408962; AA553318; AI844835; Cphn 2; Cphn2; Cyclophilin B; Cyclophilin like protein; CyP 20b; CYP S1; CYP-S1; CYPB; EC 5.2.1.8; MGC14109; MGC2224; OI9; peptidyl prolyl cis trans isomerase B; Peptidyl prolyl cis trans isomerase B precursor; Peptidyl-prolyl cis-trans isomerase B; peptidylprolyl isomerase B (cyclophilin B); Peptidylprolyl isomerase B; PPIase; PPIase B; Ppib; PPIB_HUMAN; Rotamase; Rotamase B; S cyclophilin; S-cyclophilin; SCYLP;

Immunogens

Immunogen:
Uniprot:

P23284(PPIB_HUMAN) >>Visit HPA database.

Gene(ID):
PPIB(5479)
Sequence:
MLRLSERNMKVLLAAALIAGSVFFLLLPGPSAADEKKKGPKVTVKVYFDLRIGDEDVGRVIFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTAWLDGKHVVFGKVLEGMEVVRKVESTKTDSRDKPLKDVIIADCGKIEVEKPFAIAKE

PTMs - P23284 As Substrate

Site PTM Type Enzyme
Y47 Phosphorylation
R51 Methylation
K67 Ubiquitination
T72 Phosphorylation
T81 Phosphorylation
K84 Ubiquitination
Y88 Phosphorylation
K98 Acetylation
K98 Ubiquitination
R109 Methylation
K116 Ubiquitination
R122 Methylation
K129 Methylation
K129 Ubiquitination
K131 Acetylation
K131 Ubiquitination
S139 Phosphorylation
T147 Phosphorylation
S150 Phosphorylation
K158 Ubiquitination
K165 Acetylation
K165 Ubiquitination
K171 Acetylation
S184 Phosphorylation
T185 Phosphorylation
T187 Phosphorylation
S189 Phosphorylation
C202 S-Nitrosylation
K209 Acetylation
K209 Ubiquitination
K215 Acetylation

Research Backgrounds

Function:

PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding.

Subcellular Location:

Endoplasmic reticulum lumen. Melanosome.
Note: Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065).

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Interacts with DYM. Interacts with CALR, CLGN and CANX.

Family&Domains:

Belongs to the cyclophilin-type PPIase family. PPIase B subfamily.

Restrictive clause

 

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