AFfirm™ RCAN3 Mouse Monoclonal Antibody - #BF8793

Product: RCAN3 Mouse Monoclonal Antibody
Catalog: BF8793
Description: Mouse monoclonal antibody to RCAN3
Application: WB
Reactivity: Human
Prediction: Human
Mol.Wt.: 27kD(Calculated).
Uniprot: Q9UKA8

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Mouse
Application:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Monoclonal [AFfirm8793]
Specificity:
RCAN3 Mouse Monoclonal Antibody detects endogenous levels of RCAN3.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Calcipressin-3; Down syndrome candidate region 1 like 2; Down syndrome candidate region 1 like 2; regulator of calcineurin 3; Down syndrome candidate region 1 like protein 2; Down syndrome candidate region 1-like protein 2; Down syndrome critical region gene 1 like 2; DSCR1L2; hRCN3; MCIP3; Myocyte enriched calcineurin interacting protein 3; Myocyte-enriched calcineurin-interacting protein 3; RCAN family member 3; RCAN3; RCAN3_HUMAN; RCN3; Regulator of calcineurin 3; Regulator of calcineurin 3 isoform 1b,2;

Immunogens

Immunogen:

A synthesized peptide derived from human RCAN3.

Uniprot:

Q9UKA8(RCAN3_HUMAN) >>Visit HPA database.

Gene(ID):
RCAN3(11123)
Expression:
Q9UKA8 RCAN3_HUMAN:

Highest expression in heart, skeletal muscle kidney, liver and peripheral blood leukocytes. Lower expression in all other tissues.

Sequence:
MLRDTMKSWNDSQSDLCSTDQEEEEEMIFGENEDDLDEMMDLSDLPTSLFACSVHEAVFEAREQKERFEALFTIYDDQVTFQLFKSFRRVRINFSKPEAAARARIELHETDFNGQKLKLYFAQVQMSGEVRDKSYLLPPQPVKQFLISPPASPPVGWKQSEDAMPVINYDLLCAVSKLGPGEKYELHAGTESTPSVVVHVCESETEEEEETKNPKQKIAQTRRPDPPTAALNEPQTFDCAL

Research Backgrounds

Function:

Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development (By similarity).

Tissue Specificity:

Highest expression in heart, skeletal muscle kidney, liver and peripheral blood leukocytes. Lower expression in all other tissues.

Subunit Structure:

Interacts with protein phosphatase PPP3CA/calcineurin A.

Family&Domains:

Belongs to the RCAN family.

Restrictive clause

 

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