AFfirm™ FAAH2 Mouse Monoclonal Antibody - #BF8792

Product: FAAH2 Mouse Monoclonal Antibody
Catalog: BF8792
Description: Mouse monoclonal antibody to FAAH2
Application: WB
Reactivity: Human
Prediction: Human
Mol.Wt.: 60kD; 58kD(Calculated).
Uniprot: Q6GMR7

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Mouse
Application:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Monoclonal [AFfirm8792]
Specificity:
FAAH2 Mouse Monoclonal Antibody detects endogenous levels of FAAH2.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

AMDD; amidase domain containing; amidase domain containing protein; Amidase domain-containing protein; Anandamide amidohydrolase 2; FAAH-2; FAAH2; FAAH2_HUMAN; fatty acid amide hydrolase 2; Fatty-acid amide hydrolase 2; FLJ31204; Oleamide hydrolase 2; RP11-479E16; RP11-479E16.1;

Immunogens

Immunogen:

A synthesized peptide derived from human FAAH2.

Uniprot:

Q6GMR7(FAAH2_HUMAN) >>Visit HPA database.

Gene(ID):
FAAH2(158584)
Expression:
Q6GMR7 FAAH2_HUMAN:

Highly expressed in the brain, small intestine and testis. Also expressed in the heart, kidney, liver, lung and prostate.

Sequence:
MAPSFTARIQLFLLRALGFLIGLVGRAALVLGGPKFASKTPRPVTEPLLLLSGMQLAKLIRQRKVKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKQEDEATLENKWPFLGVPLTVKEAFQLQGMPNSSGLMNRRDAIAKTDATVVALLKGAGAIPLGITNCSELCMWYESSNKIYGRSNNPYDLQHIVGGSSGGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAVGAQELFLCTGPMCRYAEDLAPMLKVMAGPGIKRLKLDTKVHLKDLKFYWMEHDGGSFLMSKVDQDLIMTQKKVVVHLETILGASVQHVKLKKMKYSFQLWIAMMSAKGHDGKEPVKFVDLLGDHGKHVSPLWELIKWCLGLSVYTIPSIGLALLEEKLRYSNEKYQKFKAVEESLRKELVDMLGDDGVFLYPSHPTVAPKHHVPLTRPFNFAYTGVFSALGLPVTQCPLGLNAKGLPLGIQVVAGPFNDHLTLAVAQYLEKTFGGWVCPGKF

Research Backgrounds

Function:

Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates.

Subcellular Location:

Membrane>Single-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Highly expressed in the brain, small intestine and testis. Also expressed in the heart, kidney, liver, lung and prostate.

Subunit Structure:

Homodimer.

Family&Domains:

Belongs to the amidase family.

Restrictive clause

 

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For Research Use Only.
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