AFfirm™ TFG Mouse Monoclonal Antibody - #BF8787

Product: TFG Mouse Monoclonal Antibody
Catalog: BF8787
Description: Mouse monoclonal antibody to TFG
Application: WB
Reactivity: Human
Prediction: Mouse, Rat
Mol.Wt.: 43kD(Calculated).
Uniprot: Q92734

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Mouse
Application:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Monoclonal [AFfirm8787]
Specificity:
TFG Mouse Monoclonal Antibody detects endogenous levels of TFG.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

FLJ36137; HMSNP; OTTHUMP00000214045; OTTHUMP00000214046; OTTHUMP00000214047; OTTHUMP00000214048; Protein TFG; SPG57; TF6; TFG; TFG_HUMAN; TRK fused; TRK fused gene; TRK fused gene protein; TRK-fused gene protein; TRKT3; TRKT3 oncogene;

Immunogens

Immunogen:

A synthesized peptide derived from human TFG.

Uniprot:

Q92734(TFG_HUMAN) >>Visit HPA database.

Gene(ID):
TFG(10342)
Expression:
Q92734 TFG_HUMAN:

Ubiquitous.

Sequence:
MNGQLDLSGKLIIKAQLGEDIRRIPIHNEDITYDELVLMMQRVFRGKLLSNDEVTIKYKDEDGDLITIFDSSDLSFAIQCSRILKLTLFVNGQPRPLESSQVKYLRRELIELRNKVNRLLDSLEPPGEPGPSTNIPENDTVDGREEKSASDSSGKQSTQVMAASMSAFDPLKNQDEINKNVMSAFGLTDDQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPRPGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQPGPGYR

Research Backgrounds

Function:

Plays a role in the normal dynamic function of the endoplasmic reticulum (ER) and its associated microtubules. Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.

Subcellular Location:

Endoplasmic reticulum.
Note: Localizes to endoplasmic reticulum exit site (ERES), also known as transitional endoplasmic reticulum (tER) (PubMed:27813252, PubMed:21478858).

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Ubiquitous.

Subunit Structure:

Self-associates to form an oligomeric complex. Interacts with PDCD6; promoting localization and polymerization of TFG at endoplasmic reticulum exit site. Interacts with SEC16B.

Research Fields

· Human Diseases > Cancers: Overview > Pathways in cancer.   (View pathway)

· Human Diseases > Cancers: Specific types > Thyroid cancer.   (View pathway)

Restrictive clause

 

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