Product: RPL8 Mouse Monoclonal Antibody
Catalog: BF8744
Description: Mouse monoclonal antibody to RPL8
Application: WB
Reactivity: Human
Prediction: Mouse, Rat
Mol.Wt.: 30kD; 28kD(Calculated).
Uniprot: P62917

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Product Info

Source:
Mouse
Application:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Monoclonal [AFfirm8744]
Specificity:
RPL8 Mouse Monoclonal Antibody detects endogenous levels of RPL8.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

60S ribosomal protein L8; L8; Ribosomal protein L8; RL8_HUMAN; RPL 8; rpl8;

Immunogens

Immunogen:

A synthesized peptide derived from human RPL8.

Uniprot:
Gene(ID):
Sequence:
MGRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGIVKDIIHDPGRGAPLAKVVFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKPGDRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPILKAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAARRTGRLRGTKTVQEKEN

Research Backgrounds

Function:

Component of the large ribosomal subunit.

PTMs:

Hydroxylated on His-216 by RIOX1. The modification is impaired by hypoxia.

Subcellular Location:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Component of the large ribosomal subunit (Probable). Interacts with CRY1 (By similarity).

Family&Domains:

Belongs to the universal ribosomal protein uL2 family.

Research Fields

· Genetic Information Processing > Translation > Ribosome.

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