AFfirm™ ZFPL1 Mouse Monoclonal Antibody - #BF8732

Product: ZFPL1 Mouse Monoclonal Antibody
Catalog: BF8732
Description: Mouse monoclonal antibody to ZFPL1
Application: WB
Reactivity: Human
Prediction: Mouse
Mol.Wt.: 33-40kD; 34kD(Calculated).
Uniprot: O95159

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Mouse
Application:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Monoclonal [AFfirm8732]
Specificity:
ZFPL1 Mouse Monoclonal Antibody detects endogenous levels of ZFPL1.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

D11S750; MCG4; MGC 4; ZFPL 1; Zinc finger protein like 1; Zinc finger protein MCG4; zinc-finger protein in MEN1 region;

Immunogens

Immunogen:

A synthesized peptide derived from human ZFPL1.

Uniprot:

O95159(ZFPL1_HUMAN) >>Visit HPA database.

Gene(ID):
ZFPL1(7542)
Expression:
O95159 ZFPL1_HUMAN:

Expressed strongly in the exocrine pancreas.

Sequence:
MGLCKCPKRKVTNLFCFEHRVNVCEHCLVANHAKCIVQSYLQWLQDSDYNPNCRLCNIPLASRETTRLVCYDLFHWACLNERAAQLPRNTAPAGYQCPSCNGPIFPPTNLAGPVASALREKLATVNWARAGLGLPLIDEVVSPEPEPLNTSDFSDWSSFNASSTPGPEEVDSASAAPAFYSQAPRPPASPGRPEQHTVIHMGNPEPLTHAPRKVYDTRDDDRTPGLHGDCDDDKYRRRPALGWLARLLRSRAGSRKRPLTLLQRAGLLLLLGLLGFLALLALMSRLGRAAADSDPNLDPLMNPHIRVGPS

Research Backgrounds

Function:

Required for cis-Golgi integrity and efficient ER to Golgi transport. Involved in the maintenance of the integrity of the cis-Golgi, possibly via its interaction with GOLGA2/GM130.

PTMs:

Phosphorylated.

Subcellular Location:

Golgi apparatus>cis-Golgi network membrane>Single-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed strongly in the exocrine pancreas.

Subunit Structure:

Interacts with GOLGA2/GM130.

Family&Domains:

The B box-type and RING-type zinc fingers although degenerate play a central role in function of the protein.

Belongs to the ZFPL1 family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

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