AFfirm™ VSIG4 Mouse Monoclonal Antibody - #BF8698

Product: VSIG4 Mouse Monoclonal Antibody
Catalog: BF8698
Description: Mouse monoclonal antibody to VSIG4
Application: WB
Reactivity: Human
Prediction: Rat
Mol.Wt.: 40/50kD; 44kD(Calculated).
Uniprot: Q9Y279

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 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Mouse
Application:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Monoclonal [AFfirm8698]
Specificity:
VSIG4 Mouse Monoclonal Antibody detects endogenous levels of VSIG4.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Complement receptor of the immunoglobulin superfamily; CRIg; Ig superfamily protein; Protein Z39Ig; UNQ317/PRO362; V set and immunoglobulin domain containing 4; V-set and immunoglobulin domain-containing protein 4; VSIG4; VSIG4_HUMAN; Z39IG;

Immunogens

Immunogen:

A synthesized peptide derived from human VSIG4.

Uniprot:

Q9Y279(VSIG4_HUMAN) >>Visit HPA database.

Gene(ID):
VSIG4(11326)
Expression:
Q9Y279 VSIG4_HUMAN:

Abundantly expressed in several fetal tissues. In adult tissues, highest expression in lung and placenta. Expressed in resting macrophages.

Sequence:
MGILLGLLLLGHLTVDTYGRPILEVPESVTGPWKGDVNLPCTYDPLQGYTQVLVKWLVQRGSDPVTIFLRDSSGDHIQQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLLFKPAVIADSGSYFCTAKGQVGSEQHSDIVKFVVKDSSKLLKTKTEAPTTMTYPLKATSTVKQSWDWTTDMDGYLGETSAGPGKSLPVFAIILIISLCCMVVFTMAYIMLCRKTSQQEHVYEAARAHAREANDSGETMRVAIFASGCSSDEPTSQNLGNNYSDEPCIGQEYQIIAQINGNYARLLDTVPLDYEFLATEGKSVC

Research Backgrounds

Function:

Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases.

Subcellular Location:

Membrane>Single-pass type I membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Abundantly expressed in several fetal tissues. In adult tissues, highest expression in lung and placenta. Expressed in resting macrophages.

Research Fields

· Organismal Systems > Immune system > Complement and coagulation cascades.   (View pathway)

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