AFfirm™ SLC39A12 Mouse Monoclonal Antibody - #BF8663

Product: SLC39A12 Mouse Monoclonal Antibody
Catalog: BF8663
Description: Mouse monoclonal antibody to SLC39A12
Application: WB
Reactivity: Human
Prediction: Mouse
Mol.Wt.: 70kD; 77kD(Calculated).
Uniprot: Q504Y0

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Mouse
Application:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Monoclonal [AFfirm8663]
Specificity:
SLC39A12 Mouse Monoclonal Antibody detects endogenous levels of SLC39A12.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

bA570F3.1; FLJ30499; LIV 1 subfamily of ZIP zinc transporter 8; LIV-1 subfamily of ZIP zinc transporter 8; LZT Hs8; LZT-Hs8; LZTHs8; MGC43205; MGC51099; S39AC_HUMAN; SLC39A12; Solute carrier family 39 (metal ion transporter) member 12; Solute carrier family 39 (zinc transporter) member 12; Solute carrier family 39 member 12; Zinc transporter ZIP12; ZIP 12; ZIP-12; ZIP12; Zrt and Irt like protein 12; Zrt- and Irt-like protein 12;

Immunogens

Immunogen:

A synthesized peptide derived from human SLC39A12.

Uniprot:

Q504Y0(S39AC_HUMAN) >>Visit HPA database.

Gene(ID):
SLC39A12(221074)
Expression:
Q504Y0 S39AC_HUMAN:

Expressed in brain and eye.

Sequence:
MCFRTKLSVSWVPLFLLLSRVFSTETDKPSAQDSRSRGSSGQPADLLQVLSAGDHPPHNHSRSLIKTLLEKTGCPRRRNGMQGDCNLCFEPDALLLIAGGNFEDQLREEVVQRVSLLLLYYIIHQEEICSSKLNMSNKEYKFYLHSLLSLRQDEDSSFLSQNETEDILAFTRQYFDTSQSQCMETKTLQKKSGIVSSEGANESTLPQLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSSLNRTNTLRLSELDQLLNTLWTRSTCIKNEKIHQFQRKQNNIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFILLVSPNDKQGLSLVNGHVGHSHHLALNSELSDQAGRGKSASTIQLKSPEDSQAAEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYEQNIKI

Research Backgrounds

Function:

Acts as a zinc-influx transporter (Potential). May be partly involved in the outbreak of schizophrenia.

Subcellular Location:

Membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in brain and eye.

Family&Domains:

Belongs to the ZIP transporter (TC 2.A.5) family.

Restrictive clause

 

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