SERC1 Mouse Monoclonal Antibody | Affinity Biosciences

Product:	SERC1 Mouse Monoclonal Antibody
Catalog:	BF8654
Description:	Mouse monoclonal antibody to SERC1
Application:	WB
Reactivity:	Human
Prediction:	Mouse, Rat
Mol.Wt.:	48kDa; 50kD(Calculated).
Uniprot:	Q9NRX5

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Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$280	In stock
200ul	$350	In stock

Lead Time: Same day delivery

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Related Downloads

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Mouse

Application:

WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human

Clonality:

Monoclonal [AFfirm8654]

Specificity:

SERC1 Mouse Monoclonal Antibody detects endogenous levels of total SERC1.

Conjugate:

Unconjugated.

Purification:

Affinity-chromatography.

Storage:

Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

1500011D18Rik; AI315070; AIGP 2; KIAA1253; LRRGT00191; mKIAA1253; SERC1_HUMAN; SERINC1; Serine incorporator 1; TDE1L; TDE2; TMS 2; Tms2; Tumor differentially expressed 1 protein like; Tumor differentially expressed protein 1-like; Tumor differentially expressed protein 2; UNQ396/PRO732;

Immunogens

Immunogen:

A synthesized peptide derived from human SERC1, corresponding to a region within C-terminal amino acids.

Uniprot:

Q9NRX5(SERC1_HUMAN) >>Visit HPA database.

Gene(ID):

SERINC1(57515)

Description:

SERINC1 Enhances the incorporation of serine into phosphatidylserine and sphingolipids. Belongs to the TDE1 family. Interacts with SPTLC1.

Sequence:

Q9NRX5 SERC1_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MGSVLGLCSMASWIPCLCGSAPCLLCRCCPSGNNSTVTRLIYALFLLVGVCVACVMLIPGMEEQLNKIPGFCENEKGVVPCNILVGYKAVYRLCFGLAMFYLLLSLLMIKVKSSSDPRAAVHNGFWFFKFAAAIAIIIGAFFIPEGTFTTVWFYVGMAGAFCFILIQLVLLIDFAHSWNESWVEKMEEGNSRCWYAALLSATALNYLLSLVAIVLFFVYYTHPASCSENKAFISVNMLLCVGASVMSILPKIQESQPRSGLLQSSVITVYTMYLTWSAMTNEPETNCNPSLLSIIGYNTTSTVPKEGQSVQWWHAQGIIGLILFLLCVFYSSIRTSNNSQVNKLTLTSDESTLIEDGGARSDGSLEDGDDVHRAVDNERDGVTYSYSFFHFMLFLASLYIMMTLTNWYRYEPSREMKSQWTAVWVKISSSWIGIVLYVWTLVAPLVLTNRDFD

PTMs - Q9NRX5 As Substrate

Q9NRX5

Site	PTM Type	Source
G2	Myristoylation	Uniprot
S31	Phosphorylation	Uniprot
S35	Phosphorylation	Uniprot
T36	Phosphorylation	Uniprot
T38	Phosphorylation	Uniprot
N298	N-Glycosylation	Uniprot
K343	Ubiquitination	Uniprot
T345	Phosphorylation	Uniprot
T347	Phosphorylation	Uniprot
S348	Phosphorylation	Uniprot
S351	Phosphorylation	Uniprot
T352	Phosphorylation	Uniprot
S361	Phosphorylation	Uniprot
S364	Phosphorylation	Uniprot
Y410	Phosphorylation	Uniprot
S413	Phosphorylation	Uniprot
S418	Phosphorylation	Uniprot
T421	Phosphorylation	Uniprot

Research Backgrounds

Q9NRX5_SERC1_HUMAN

Function:

Enhances the incorporation of serine into phosphatidylserine and sphingolipids.

Subcellular Location:

Endoplasmic reticulum membrane>Multi-pass membrane protein.

Subunit Structure:

Interacts with SPTLC1.

Family&Domains:

Belongs to the TDE1 family.

Restrictive clause

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.

AFfirm™ SERC1 Mouse Monoclonal Antibody - #BF8654