SCNM1 Mouse Monoclonal Antibody | Affinity Biosciences

Product:	SCNM1 Mouse Monoclonal Antibody
Catalog:	BF8652
Description:	Mouse monoclonal antibody to SCNM1
Application:	WB
Reactivity:	Human
Prediction:	Rat, Bovine, Horse, Sheep, Monkey
Mol.Wt.:	26 kDa; 26kD(Calculated).
Uniprot:	Q9BWG6

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Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$280	In stock
200ul	$350	In stock

Lead Time: Same day delivery

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Local distributors

Related Downloads

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Mouse

Application:

WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human

Clonality:

Monoclonal [AFfirm8652]

Specificity:

SCNM1 Mouse Monoclonal Antibody detects endogenous levels of total SCNM1.

Conjugate:

Unconjugated.

Purification:

Affinity-chromatography.

Storage:

Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

SCNM 1; Sodium channel modifier 1;

Immunogens

Immunogen:

Uniprot:

Q9BWG6(SCNM1_HUMAN) >>Visit HPA database.

Gene(ID):

SCNM1(100534012)

Sequence:

Q9BWG6 SCNM1_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MSFKREGDDWSQLNVLKKRRVGDLLASYIPEDEALMLRDGRFACAICPHRPVLDTLAMLTAHRAGKKHLSSLQLFYGKKQPGKERKQNPKHQNELRREETKAEAPLLTQTRLITQSALHRAPHYNSCCRRKYRPEAPGPSVSLSPMPPSEVKLQSGKISREPEPAAGPQAEESATVSAPAPMSPTRRRALDHYLTLRSSGWIPDGRGRWVKDENVEFDSDEEEPPDLPLD

PTMs - Q9BWG6 As Substrate

Q9BWG6

Site	PTM Type	Source
S2	Phosphorylation	Uniprot
K17	Ubiquitination	Uniprot
Y76	Phosphorylation	Uniprot
K101	Ubiquitination	Uniprot
S126	Phosphorylation	Uniprot
S144	Phosphorylation	Uniprot
S159	Phosphorylation	Uniprot
S183	Phosphorylation	Uniprot
Y193	Phosphorylation	Uniprot
T195	Phosphorylation	Uniprot
S219	Phosphorylation	Uniprot

Research Backgrounds

Q9BWG6_SCNM1_HUMAN

Function:

Plays a role in alternative splicing of pre-mRNAs, possibly by contributing to the selection of non-consensus donor sites.

Subcellular Location:

Nucleus>Nucleoplasm. Nucleus speckle.
Note: Colocalizes with LUC7L2 and SNRNP70 in nuclear speckles.

Subunit Structure:

Interacts with spliceosomal Sm proteins. Interacts with LUC7L2 and SNRNP70, which suggests a role as a spliceosome component (By similarity).

Restrictive clause

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.

AFfirm™ SCNM1 Mouse Monoclonal Antibody - #BF8652