AFfirm™ CEP27 Mouse Monoclonal Antibody - #BF8644

Product: CEP27 Mouse Monoclonal Antibody
Catalog: BF8644
Description: Mouse monoclonal antibody to CEP27
Application: WB
Reactivity: Human
Prediction: Rat, Pig, Bovine, Sheep
Mol.Wt.: 27 kDa; 27kD(Calculated).
Uniprot: Q9NVX0

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Related Downloads
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Mouse
Application:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Monoclonal [AFfirm8644]
Specificity:
CEP27 Mouse Monoclonal Antibody detects endogenous levels of total CEP27.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

C15orf25; Centrosomal protein 27 kDa; Centrosomal protein of 27 kDa; CEP27; Chromosome 15 open reading frame 25; FLJ10460; HAUS augmin-like complex subunit 2; Haus2; HAUS2_HUMAN; HsT17025;

Immunogens

Immunogen:
Uniprot:

Q9NVX0(HAUS2_HUMAN) >>Visit HPA database.

Gene(ID):
HAUS2(55142)
Sequence:
MAAANPWDPASAPNGAGLVLGHFIASGMVNQEMLNMSKKTVSCFVNFTRLQQITNIQAEIYQKNLEIELLKLEKDTADVVHPFFLAQKCHTLQSMNNHLEAVLKEKRSLRQRLLKPMCQENLPIEAVYHRYMVHLLELAVTFIERLETHLETIRNIPHLAANLKKMNQALAKMDILVTETEELAENILKWRKQQNEVSSCIPKILAEESYLYKHDIIMPPLPFTSKVHVQTINAK

PTMs - Q9NVX0 As Substrate

Site PTM Type Enzyme
S37 Phosphorylation
K39 Ubiquitination
K63 Ubiquitination
K71 Ubiquitination
K74 Ubiquitination
K88 Ubiquitination
K104 Ubiquitination
K115 Ubiquitination
K192 Ubiquitination
K203 Ubiquitination
Y210 Phosphorylation
K213 Ubiquitination
K226 Ubiquitination

Research Backgrounds

Function:

Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.

Subcellular Location:

Cytoplasm>Cytoskeleton>Microtubule organizing center>Centrosome. Cytoplasm>Cytoskeleton>Spindle.
Note: Localizes to interphase centrosomes and to mitotic spindle microtubules.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Component of the HAUS augmin-like complex. The complex interacts with the gamma-tubulin ring complex and this interaction is required for spindle assembly.

Family&Domains:

Belongs to the HAUS2 family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

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