AFfirm™ ALDH3B2 Mouse Monoclonal Antibody - #BF8640
Product Info
Source:
Mouse
Application:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Reactivity:
Human
Clonality:
Monoclonal [AFfirm8640]
Specificity:
ALDH3B2 Mouse Monoclonal Antibody detects endogenous levels of total ALDH3B2.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:
Fold/Unfold
Acetaldehyde dehydrogenase 8; AL3B2_HUMAN; Aldehyde dehydrogenase 3 family, member B2; Aldehyde dehydrogenase 8; Aldehyde dehydrogenase family 3 member B2; ALDH3B2; ALDH8; OTTHUMP00000235616;
Immunogens
Immunogen:
Uniprot:
Expression:
Sequence:
- P48448 AL3B2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKDEPRSTNLFMKLDSVFIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEVLPQYLDQSCFAVVLGGPQETGQLLEHKLDYIFFTGSPRVGKIVMTAATKHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYGDDPQSSPNLGHIINQKQFQRLRALLGCSRVAIGGQSNESDRYIAPTVLVDVQETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSSGSFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLAPSGLEKLKEIHYPPYTDWNQQLLRWGMGSQSCTLL
PTMs - P48448 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T117 | Phosphorylation | Uniprot | |
| T124 | Phosphorylation | Uniprot | |
| T127 | Phosphorylation | Uniprot | |
| K133 | Ubiquitination | Uniprot | |
| K208 | Ubiquitination | Uniprot | |
| Y362 | Phosphorylation | Uniprot | |
| Y365 | Phosphorylation | Uniprot |
Research Backgrounds
Function:
Oxidizes medium and long chain aldehydes into non-toxic fatty acids.
PTMs:
Geranylgeranylation is important for localization to lipid droplets and enzyme activity.
Subcellular Location:
Lipid droplet.
Tissue Specificity:
Salivary gland.
Family&Domains:
Belongs to the aldehyde dehydrogenase family.
Restrictive clause
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For Research Use Only.
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