AFfirm™ NAA40 Mouse Monoclonal Antibody - #BF8579

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Product: NAA40 Mouse Monoclonal Antibody
Catalog: BF8579
Description: Mouse monoclonal antibody to NAA40
Application: WB
Reactivity: Human, Rat
Mol.Wt.: 27kD; 27kD(Calculated).
Uniprot: Q86UY6

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 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Mouse
Application:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Rat
Clonality:
Monoclonal [AFfirm8579]
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

N acetyltransferase 11 (GCN5 related, putative); N alpha acetyl transferase 40; N alpha acetyltransferase 40; N(alpha) acetyltransferase 40; N(alpha) acetyltransferase 40, NatD catalytic subunit, homolog; N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae); N-acetyltransferase 11; N-alpha-acetyltransferase 40, NatD catalytic subunit; naa40; NAA40_HUMAN; NAT11; NatD catalytic subunit; PATT1;

Immunogens

Immunogen:

A synthesized peptide derived from Human NAA40.

Uniprot:

Q86UY6(NAA40_HUMAN) >>Visit HPA database.

Gene(ID):
NAA40(79829)
Expression:
Q86UY6 NAA40_HUMAN:

Widely expressed; with the highest expression level in liver and the lowest expression in brain (at protein level).

Sequence:
MGRKSSKAKEKKQKRLEERAAMDAVCAKVDAANRLGDPLEAFPVFKKYDRNGLNVSIECKRVSGLEPATVDWAFDLTKTNMQTMYEQSEWGWKDREKREEMTDDRAWYLIAWENSSVPVAFSHFRFDVECGDEVLYCYEVQLESKVRRKGLGKFLIQILQLMANSTQMKKVMLTVFKHNHGAYQFFREALQFEIDDSSPSMSGCCGEDCSYEILSRRTKFGDSHHSHAGGHCGGCCH

Research Backgrounds

Function:

N-alpha-acetyltransferase that specifically mediates the acetylation of the N-terminal residues of histones H4 and H2A. In contrast to other N-alpha-acetyltransferase, has a very specific selectivity for histones H4 and H2A N-terminus and specifically recognizes the 'Ser-Gly-Arg-Gly sequence'. Acts as a negative regulator of apoptosis. May play a role in hepatic lipid metabolism (By similarity).

Subcellular Location:

Cytoplasm. Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Widely expressed; with the highest expression level in liver and the lowest expression in brain (at protein level).

Family&Domains:

Belongs to the acetyltransferase family. NAA40 subfamily.

Restrictive clause

 

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