SSH3 Mouse Monoclonal Antibody | Affinity Biosciences

Product:	SSH3 Mouse Monoclonal Antibody
Catalog:	BF8560
Description:	Mouse monoclonal antibody to SSH3
Application:	WB
Reactivity:	Human
Prediction:	Pig, Bovine, Sheep, Dog
Mol.Wt.:	74KD; 73kD(Calculated).
Uniprot:	Q8TE77

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Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$175 ~~350~~	In stock

Related Downloads

MS Report

HPLC Report

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Mouse

Application:

WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human

Clonality:

Monoclonal [AFfirm8560]

Conjugate:

Unconjugated.

Purification:

Affinity-chromatography.

Storage:

Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

FLJ10928; FLJ20515; hSSH 3L; hSSH-3L; hSSH3L; Protein phosphatase Slingshot homolog 3; Slingshot 3; Slingshot homolog 3; Slingshot3; SSH 3; SSH 3L; SSH-3L; SSH-like protein 3; Ssh3; SSH3_HUMAN; SSH3L;

Immunogens

Immunogen:

Uniprot:

Q8TE77(SSH3_HUMAN) >>Visit HPA database.

Gene(ID):

SSH3(54961)

Sequence:

Q8TE77 SSH3_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MALVTVSRSPPGSGASTPVGPWDQAVQRRSRLQRRQSFAVLRGAVLGLQDGGDNDDAAEASSEPTEKAPSEEELHGDQTDFGQGSQSPQKQEEQRQHLHLMVQLLRPQDDIRLAAQLEAPRPPRLRYLLVVSTREGEGLSQDETVLLGVDFPDSSSPSCTLGLVLPLWSDTQVYLDGDGGFSVTSGGQSRIFKPISIQTMWATLQVLHQACEAALGSGLVPGGSALTWASHYQERLNSEQSCLNEWTAMADLESLRPPSAEPGGSSEQEQMEQAIRAELWKVLDVSDLESVTSKEIRQALELRLGLPLQQYRDFIDNQMLLLVAQRDRASRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGILTASRQSHVWEQKVGGVSPEEHPAPEVSTPFPPLPPEPEGGGEEKVVGMEESQAAPKEEPGPRPRINLRGVMRSISLLEPSLELESTSETSDMPEVFSSHESSHEEPLQPFPQLARTKGGQQVDRGPQPALKSRQSVVTLQGSAVVANRTQAFQEQEQGQGQGQGEPCISSTPRFRKVVRQASVHDSGEEGEA

PTMs - Q8TE77 As Substrate

Q8TE77

Site	PTM Type	Enzyme	Source
T5	Phosphorylation		Uniprot
S9	Phosphorylation		Uniprot
S13	Phosphorylation		Uniprot
S16	Phosphorylation		Uniprot
T17	Phosphorylation		Uniprot
S37	Phosphorylation	Q96GD4 (AURKB)	Uniprot
K67	Acetylation		Uniprot
S70	Phosphorylation		Uniprot
T79	Phosphorylation		Uniprot
S85	Phosphorylation		Uniprot
S87	Phosphorylation		Uniprot
K90	Ubiquitination		Uniprot
S259	Phosphorylation		Uniprot
K281	Ubiquitination		Uniprot
S290	Phosphorylation		Uniprot
T292	Phosphorylation		Uniprot
S293	Phosphorylation		Uniprot
K294	Ubiquitination		Uniprot
S385	Phosphorylation		Uniprot
S484	Phosphorylation		Uniprot
K523	Sumoylation		Uniprot
S547	Phosphorylation		Uniprot
K598	Methylation		Uniprot
S602	Phosphorylation		Uniprot
T605	Phosphorylation		Uniprot
S609	Phosphorylation		Uniprot
S637	Phosphorylation		Uniprot
T638	Phosphorylation		Uniprot
S649	Phosphorylation		Uniprot
S653	Phosphorylation		Uniprot

Research Backgrounds

Q8TE77_SSH3_HUMAN

Function:

Protein phosphatase which may play a role in the regulation of actin filament dynamics. Can dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly (By similarity).

Subcellular Location:

Cytoplasm>Cytoskeleton. Nucleus.

Subunit Structure:

Does not bind to, or colocalize with, filamentous actin.

Family&Domains:

Belongs to the protein-tyrosine phosphatase family.

Research Fields

· Cellular Processes > Cell motility > Regulation of actin cytoskeleton. (View pathway)

· Organismal Systems > Development > Axon guidance. (View pathway)

Restrictive clause

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For Research Use Only.
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AFfirm™ SSH3 Mouse Monoclonal Antibody - #BF8560