AFfirm™ RHPN1 Mouse Monoclonal Antibody - #BF8545
Product Info
Source:
Mouse
Application:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Reactivity:
Human
Clonality:
Monoclonal [AFfirm8545]
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:
Fold/Unfold
GTP Rho binding protein 1; GTP-Rho-binding protein 1; ODF5; Outer dense fiber of sperm tails 5; Rhophilin 1; Rhophilin-1; RHPN; Rhpn1; RHPN1_HUMAN;
Immunogens
Immunogen:
Uniprot:
Gene(ID):
Sequence:
- Q8TCX5 RHPN1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MILEERPDGAGAGEESPRLQGCDSLTQIQCGQLQSRRAQIHQQIDKELQMRTGAENLYRATSNNRVRETVALELSYVNSNLQLLKEELEELSGGVDPGRHGSEAVTVPMIPLGLKETKELDWSTPLKELISVHFGEDGASYEAEIRELEALRQAMRTPSRNESGLELLTAYYNQLCFLDARFLTPARSLGLFFHWYDSLTGVPAQQRALAFEKGSVLFNIGALHTQIGARQDRSCTEGARRAMEAFQRAAGAFSLLRENFSHAPSPDMSAASLCALEQLMMAQAQECVFEGLSPPASMAPQDCLAQLRLAQEAAQVAAEYRLVHRTMAQPPVHDYVPVSWTALVHVKAEYFRSLAHYHVAMALCDGSPATEGELPTHEQVFLQPPTSSKPRGPVLPQELEERRQLGKAHLKRAILGQEEALRLHALCRVLREVDLLRAVISQTLQRSLAKYAELDREDDFCEAAEAPDIQPKTHQKPEARMPRLSQGKGPDIFHRLGPLSVFSAKNRWRLVGPVHLTRGEGGFGLTLRGDSPVLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVTELKAAGEAGASLQVVSLLPSSRLPSLGDRRPVLLGPRGLLRSQREHGCKTPASTWASPRPLLNWSRKAQQGKTGGCPQPCAPVKPAPPSSLKHPGWP
PTMs - Q8TCX5 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S16 | Phosphorylation | Uniprot | |
| S24 | Phosphorylation | Uniprot | |
| T26 | Phosphorylation | Uniprot | |
| S92 | Phosphorylation | Uniprot | |
| K118 | Ubiquitination | Uniprot | |
| T157 | Phosphorylation | Uniprot | |
| S159 | Phosphorylation | Uniprot | |
| S163 | Phosphorylation | Uniprot | |
| S188 | Phosphorylation | Uniprot | |
| K411 | Acetylation | Uniprot | |
| K450 | Ubiquitination | Uniprot | |
| K505 | Ubiquitination | Uniprot | |
| R632 | Methylation | Uniprot |
Research Backgrounds
Function:
Has no enzymatic activity. May serve as a target for Rho, and interact with some cytoskeletal component upon Rho binding or relay a Rho signal to other molecules.
Subunit Structure:
Binds specifically to GTP-Rho. Interacts with ROPN1.
Family&Domains:
The PDZ domain mediates interaction with ROPN1.
Belongs to the RHPN family.
Restrictive clause
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For Research Use Only.
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