Product: PPP1R7 Mouse Monoclonal Antibody
Catalog: BF8538
Description: Mouse monoclonal antibody to PPP1R7
Application: WB IHC
Reactivity: Human, Rat
Prediction: Pig, Bovine, Rabbit
Mol.Wt.: 48 KD; 42kD(Calculated).
Uniprot: Q15435

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Product Info

Source:
Mouse
Application:
WB 1:500-1:3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Rat
Clonality:
Monoclonal [AFfirm8538]
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

MGC105784; PP1R7_HUMAN; PPP1R7; protein phosphatase 1 regulatory (inhibitor) subunit 7; Protein phosphatase 1 regulatory subunit 22; Protein phosphatase 1 regulatory subunit 7 alpha2; Protein phosphatase 1 regulatory subunit 7; Protein phosphatase 1 regulatory subunit 7 beta1; Protein phosphatase 1 regulatory subunit 7 beta2; SDS 22; SDS22;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q15435 PP1R7_HUMAN:

Widely expressed.

Sequence:
MAAERGAGQQQSQEMMEVDRRVESEESGDEEGKKHSSGIVADLSEQSLKDGEERGEEDPEEEHELPVDMETINLDRDAEDVDLNHYRIGKIEGFEVLKKVKTLCLRQNLIKCIENLEELQSLRELDLYDNQIKKIENLEALTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLESWSDLDELKGARSLETVYLERNPLQKDPQYRRKVMLALPSVRQIDATFVRF

PTMs - Q15435 As Substrate

Site PTM Type Enzyme
A2 Acetylation
S12 Phosphorylation
S24 Phosphorylation
S27 Phosphorylation
K34 Acetylation
S36 Phosphorylation
S37 Phosphorylation
S44 Phosphorylation
S47 Phosphorylation
K49 Ubiquitination
R54 Methylation
R76 Methylation
K90 Ubiquitination
K98 Ubiquitination
K101 Ubiquitination
K111 Ubiquitination
K133 Ubiquitination
K162 Ubiquitination
K167 Ubiquitination
K168 Ubiquitination
K175 Ubiquitination
K178 Ubiquitination
K217 Ubiquitination
K219 Ubiquitination
K222 Ubiquitination
T243 Phosphorylation
K244 Ubiquitination
T277 Phosphorylation
S322 Phosphorylation
Y327 Phosphorylation
K335 Ubiquitination

Research Backgrounds

Function:

Regulatory subunit of protein phosphatase 1.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Widely expressed.

Subunit Structure:

Interacts with PPP1CA, PPP1CB and PPP1CC/PPP1G isoform 1.

Family&Domains:

Belongs to the SDS22 family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.