AFfirm™ SDF4 Mouse Monoclonal Antibody - #BF8500

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Product: SDF4 Mouse Monoclonal Antibody
Catalog: BF8500
Description: Mouse monoclonal antibody to SDF4
Application: WB IHC
Reactivity: Human
Mol.Wt.: 30~40kD; 42kD(Calculated).
Uniprot: Q9BRK5

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Mouse
Application:
WB 1:500-1:3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Monoclonal [AFfirm8500]
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

45 kDa calcium-binding protein; Cab45; CAB45_HUMAN; Calcium binding protein; PSEC0034; SDF 4; SDF-4; SDF4; Stromal cell derived factor 4; Stromal cell-derived factor 4;

Immunogens

Immunogen:

A synthesized peptide derived from Human SDF4.

Uniprot:

Q9BRK5(CAB45_HUMAN) >>Visit HPA database.

Gene(ID):
SDF4(51150)
Expression:
Q9BRK5 CAB45_HUMAN:

Ubiquitous. Isoform 5 is expressed in pancreas.

Sequence:
MVWPWVAMASRWGPLIGLAPCCLWLLGAVLLMDASARPANHSSTRERVANREENEILPPDHLNGVKLEMDGHLNRGFHQEVFLGKDLGGFDEDAEPRRSRRKLMVIFSKVDVNTDRKISAKEMQRWIMEKTAEHFQEAMEESKTHFRAVDPDGDGHVSWDEYKVKFLASKGHSEKEVADAIRLNEELKVDEETQEVLENLKDRWYQADSPPADLLLTEEEFLSFLHPEHSRGMLRFMVKEIVRDLDQDGDKQLSVPEFISLPVGTVENQQGQDIDDNWVKDRKKEFEELIDSNHDGIVTAEELESYMDPMNEYNALNEAKQMIAVADENQNHHLEPEEVLKYSEFFTGSKLVDYARSVHEEF

Research Backgrounds

Function:

May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment.

Isoform 5 may be involved in the exocytosis of zymogens by pancreatic acini.

Subcellular Location:

Golgi apparatus lumen.

Cytoplasm. Cell membrane. Cell projection>Bleb.
Note: Isoform 5 colocalizes with STX3 and STXBP1 isoform 2 at the plasma membrane and cell surface blebs.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Ubiquitous. Isoform 5 is expressed in pancreas.

Subunit Structure:

Isoform 5 interacts with STXBP1; the interaction is enhanced in presence of calcium. Isoform 5 interacts with STX3.

Family&Domains:

Binds calcium via its EF-hands (By similarity). Isoform 5 binds calcium.

Belongs to the CREC family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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