AFfirm™ RXFP1 Mouse Monoclonal Antibody - #BF8442
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Fold/Unfold
Gm1018; Leucine rich repeat containing G protein coupled receptor 7; Leucine-rich repeat-containing G-protein coupled receptor 7; LGR 7; LGR7; LGR7.1; LGR7.10; LGR7.2; MGC138347; MGC142177; Relaxin family peptide receptor 1; Relaxin receptor 1; Relaxin/insulin like family peptide receptor 1; RXFP 1; RXFP1; RXFP1_HUMAN;
Immunogens
Expressed in the brain, kidney, testis, placenta, uterus, ovary, adrenal, prostate, skin and heart. Not detected in spleen.
- Q9HBX9 RXFP1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTSGSVFFYILIFGKYFSHGGGQDVKCSLGYFPCGNITKCLPQLLHCNGVDDCGNQADEDNCGDNNGWSLQFDKYFASYYKMTSQYPFEAETPECLVGSVPVQCLCQGLELDCDETNLRAVPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQRMFRPLMNLSHIYFKKFQYCGYAPHVRSCKPNTDGISSLENLLASIIQRVFVWVVSAVTCFGNIFVICMRPYIRSENKLYAMSIISLCCADCLMGIYLFVIGGFDLKFRGEYNKHAQLWMESTHCQLVGSLAILSTEVSVLLLTFLTLEKYICIVYPFRCVRPGKCRTITVLILIWITGFIVAFIPLSNKEFFKNYYGTNGVCFPLHSEDTESIGAQIYSVAIFLGINLAAFIIIVFSYGSMFYSVHQSAITATEIRNQVKKEMILAKRFFFIVFTDALCWIPIFVVKFLSLLQVEIPGTITSWVVIFILPINSALNPILYTLTTRPFKEMIHRFWYNYRQRKSMDSKGQKTYAPSFIWVEMWPLQEMPPELMKPDLFTYPCEMSLISQSTRLNSYS
PTMs - Q9HBX9 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| N36 | N-Glycosylation | Uniprot | |
| N127 | N-Glycosylation | Uniprot | |
| N264 | N-Glycosylation | Uniprot | |
| N272 | N-Glycosylation | Uniprot | |
| S304 | Phosphorylation | Uniprot | |
| N325 | N-Glycosylation | Uniprot | |
| N368 | N-Glycosylation | Uniprot | |
| T504 | Phosphorylation | Uniprot | |
| T507 | Phosphorylation | Uniprot |
Research Backgrounds
Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.
Cell membrane>Multi-pass membrane protein.
Expressed in the brain, kidney, testis, placenta, uterus, ovary, adrenal, prostate, skin and heart. Not detected in spleen.
Interacts with C1QTNF8.
Belongs to the G-protein coupled receptor 1 family.
Research Fields
· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.
· Organismal Systems > Endocrine system > Relaxin signaling pathway.
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