SULT1A1 Mouse Monoclonal Antibody | Affinity Biosciences

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Western blot analysis of extracts from rat heart tissue, using SULT1A1 Mouse Monoclonal Antibody.

Product:	SULT1A1 Mouse Monoclonal Antibody
Catalog:	BF8080
Description:	Mouse monoclonal antibody to SULT1A1
Application:	WB
Reactivity:	Human, Rat
Mol.Wt.:	34kDa; 34kD(Calculated).
Uniprot:	P50225

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Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$280	In stock
200ul	$350	In stock

Lead Time: Same day delivery

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Related Downloads

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Mouse

Application:

WB 1:1000-1:10000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human,Rat

Clonality:

Monoclonal [AFfirm8080]

Specificity:

SULT1A1 Antibody detects endogenous levels of total SULT1A1.

Conjugate:

Unconjugated.

Purification:

Affinity-chromatography.

Storage:

Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

Aryl sulfotransferase 1; HAST1/HAST2; Human aryl sulfotransferase mRNA complete cds; MGC131921; MGC5163; OTTHUMP00000162568; OTTHUMP00000162569; P PST 1; P PST; P-PST 1; Phenol sulfating phenol sulfotransferase 1; Phenol sulfotransferase 1; Phenol-sulfating phenol sulfotransferase 1; PST; ST1A1; ST1A1_HUMAN; ST1A3; STP; STP1; Sulfotransferase 1A1; Sulfotransferase family 1A phenol preferring member 1; Sulfotransferase family cytosolic 1A phenol preferring member 1; Sulfotransferase phenol preferring 1; SULT1A1; Thermostable phenol sulfotransferase; Thermostable phenol sulfotransferase1; Ts-PST; TSPST1;

Immunogens

Immunogen:

Uniprot:

P50225(ST1A1_HUMAN) >>Visit HPA database.

Gene(ID):

SULT1A1(6817)

Expression:

P50225 ST1A1_HUMAN:

Liver, lung, adrenal, brain, platelets and skin.

Description:

SULT1A1, also named as ST1A1, P-PST 1, ST1A3, Ts-PST, P-PST 1, STP and STP1, belongs to the sulfotransferase 1 family. It catalyzes the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. SULT1A1 is also responsible for the sulfation and activation of minoxidil. It mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk. SULT1A1 is one of two phenol sulfotransferases with thermostable enzyme activity.

Sequence:

P50225 ST1A1_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVVYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNYTTVPQEFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL

PTMs - P50225 As Substrate

P50225

Site	PTM Type	Source
K16	Ubiquitination	Uniprot
S49	Phosphorylation	Uniprot
K69	Ubiquitination	Uniprot
K85	Ubiquitination	Uniprot
T95	Phosphorylation	Uniprot
K97	Ubiquitination	Uniprot
K106	Acetylation	Uniprot
K106	Ubiquitination	Uniprot
T107	Phosphorylation	Uniprot
K122	Ubiquitination	Uniprot
K124	Ubiquitination	Uniprot
S138	Phosphorylation	Uniprot
Y140	Phosphorylation	Uniprot
Y193	Phosphorylation	Uniprot
K230	Acetylation	Uniprot
K283	Ubiquitination	Uniprot
S288	Phosphorylation	Uniprot
S290	Phosphorylation	Uniprot

Research Backgrounds

P50225_ST1A1_HUMAN

Function:

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Has also estrogen sulfotransferase activity. responsible for the sulfonation and activation of minoxidil. Is Mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk.

Subcellular Location:

Cytoplasm.

Tissue Specificity:

Liver, lung, adrenal, brain, platelets and skin.

Subunit Structure:

Homodimer.

Family&Domains:

Belongs to the sulfotransferase 1 family.

Research Fields

· Human Diseases > Cancers: Overview > Chemical carcinogenesis.

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