AFfirm™ AKR1CL2 Mouse Monoclonal Antibody - #BF8061

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Product: AKR1CL2 Mouse Monoclonal Antibody
Catalog: BF8061
Description: Mouse monoclonal antibody to AKR1CL2
Application: WB
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Sheep, Rabbit
Mol.Wt.: 37 KD; 37kD(Calculated).
Uniprot: Q96JD6

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 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

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Related Downloads
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Mouse
Application:
WB 1:1000-1:10000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Monoclonal [AFfirm8061]
Specificity:
AKR1CL2 Antibody detects endogenous levels of total AKR1CL2.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

1; 1,5-anhydro-D-fructose reductase; 5-anhydro-D-fructose reductase; AF reductase; AKCL2_HUMAN; AKR1CL2; Akr1e2; AKRDC1; Aldo keto reductase family 1 member C like protein 2; Aldo-keto reductase family 1 member C-like protein 2; Aldo-keto reductase family 1 member E2; HTSP; LoopADR; Testis specific protein; Testis-specific protein;

Immunogens

Immunogen:
Uniprot:

Q96JD6(AKCL2_HUMAN) >>Visit HPA database.

Gene(ID):
AKR1E2(83592)
Expression:
Q96JD6 AKCL2_HUMAN:

Specifically expressed in testis (PubMed:12604216, PubMed:15118078). Expressed in testicular germ cells and testis interstitial cells (PubMed:15118078).

Sequence:
MGDIPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCEGVDLIDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRLAMFPITKNHKDYPFHIEY

PTMs - Q96JD6 As Substrate

Site PTM Type Enzyme
K183 Ubiquitination
T218 Phosphorylation

Research Backgrounds

Function:

Catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol (By similarity). Has low NADPH-dependent reductase activity towards 9,10-phenanthrenequinone (in vitro).

Subcellular Location:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Specifically expressed in testis. Expressed in testicular germ cells and testis interstitial cells.

Subunit Structure:

Monomer.

Family&Domains:

Belongs to the aldo/keto reductase family.

Restrictive clause

 

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