AFfirm™ TRIM59 Mouse Monoclonal Antibody - #BF8055

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Product: TRIM59 Mouse Monoclonal Antibody
Catalog: BF8055
Description: Mouse monoclonal antibody to TRIM59
Application: WB IHC IF/ICC
Reactivity: Human, Mouse
Prediction: Pig, Bovine, Horse, Dog
Mol.Wt.: 47 KD; 47kD(Calculated).
Uniprot: Q8IWR1

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 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

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Related Downloads
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Mouse
Application:
WB 1:1000-1:10000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Monoclonal [AFfirm8055]
Specificity:
TRIM59 Antibody detects endogenous levels of total TRIM59.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

2310035M22Rik; 2700022F13Rik; MGC129860; MGC129861; MGC26631; MRF1; RING finger protein 104; RNF104; TRI59_HUMAN; TRIM57; TRIM59; Tripartite motif containing 57; tripartite motif containing 59; Tripartite motif-containing protein 59; TSBF1; Tumor suppressor TSBF 1; Tumor suppressor TSBF-1;

Immunogens

Immunogen:
Uniprot:

Q8IWR1(TRI59_HUMAN) >>Visit HPA database.

Gene(ID):
TRIM59(286827)
Sequence:
MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCRSITEIAPTGIESLPVNFALRAIIEKYQQEDHPDIVTCPEHYRQPLNVYCLLDKKLVCGHCLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEKMIQGDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKEIREQQLELMALTISLQEESPLKFLEKVDDVRQHVQILKQRPLPEVQPVEIYPRVSKILKEEWSRTEIGQIKNVLIPKMKISPKRMSCSWPGKDEKEVEFLKILNIVVVTLISVILMSILFFNQHIITFLSEITLIWFSEASLSVYQSLSNSLHKVKNILCHIFYLLKEFVWKIVSH

PTMs - Q8IWR1 As Substrate

Site PTM Type Enzyme
K176 Ubiquitination
K253 Ubiquitination
Y278 Phosphorylation
K298 Ubiquitination
S308 Phosphorylation
K310 Acetylation

Research Backgrounds

Function:

May serve as a multifunctional regulator for innate immune signaling pathways.

Subcellular Location:

Endoplasmic reticulum membrane>Single-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Interacts with ECSIT.

Family&Domains:

Belongs to the TRIM/RBCC family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.