AFfirm™ FOXJ1 Mouse Monoclonal Antibody - #BF8040

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Product: FOXJ1 Mouse Monoclonal Antibody
Catalog: BF8040
Description: Mouse monoclonal antibody to FOXJ1
Application: WB
Reactivity: Human
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog
Mol.Wt.: 60kDa; 45kD(Calculated).
Uniprot: Q92949

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 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

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Related Downloads
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Mouse
Application:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Monoclonal [AFfirm8040(AFP21836)]
Specificity:
FOXJ1 Antibody detects endogenous levels of total FOXJ1.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

FKHL13; Forkhead box J1; Forkhead box protein J1; Forkhead Homologue 4; Forkhead related protein FKHL13; Forkhead-related protein FKHL13; Fox J1; Foxj1; FOXJ1_HUMAN; Hepatocyte nuclear factor 3 forkhead homolog 4; HFH 4; HFH-4; HFH4; HNF 3/forkhead homolog 4; MGC35202;

Immunogens

Immunogen:

A synthesized peptide derived from human FOXJ1, corresponding to a region within the internal amino acids.

Uniprot:

Q92949(FOXJ1_HUMAN) >>Visit HPA database.

Gene(ID):
FOXJ1(2302)
Expression:
Q92949 FOXJ1_HUMAN:

Testis, oviduct, lung and brain cortex.

Description:
FOXJ1 May play an important role in cell fate determination during lung development and in spermatogenesis. Note:
Sequence:
MAESWLRLSGAGPAEEAGPEGGLEEPDALDDSLTSLQWLQEFSILNAKAPALPPGGTDPHGYHQVPGSAAPGSPLAADPACLGQPHTPGKPTSSCTSRSAPPGLQAPPPDDVDYATNPHVKPPYSYATLICMAMQASKATKITLSAIYKWITDNFCYFRHADPTWQNSIRHNLSLNKCFIKVPREKDEPGKGGFWRIDPQYAERLLSGAFKKRRLPPVHIHPAFARQAAQEPSAVPRAGPLTVNTEAQQLLREFEEATGEAGWGAGEGRLGHKRKQPLPKRVAKVPRPPSTLLPTPEEQGELEPLKGNFDWEAIFDAGTLGGELGALEALELSPPLSPASHVDVDLTIHGRHIDCPATWGPSVEQAADSLDFDETFLATSFLQHPWDESGSGCLPPEPLFEAGDATLASDLQDWASVGAFL

PTMs - Q92949 As Substrate

Site PTM Type Enzyme
S174 Phosphorylation

Research Backgrounds

Function:

Transcription factor specifically required for the formation of motile cilia. Acts by activating transcription of genes that mediate assembly of motile cilia, such as CFAP157. Binds the DNA consensus sequences 5'-HWDTGTTTGTTTA-3' or 5'-KTTTGTTGTTKTW-3' (where H is not G, W is A or T, D is not C, and K is G or T). Activates the transcription of a variety of ciliary proteins in the developing brain and lung.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Testis, oviduct, lung and brain cortex.

Family&Domains:

Belongs to the FOXJ1 family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

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