AFfirm™ SIGLEC15 Mouse Monoclonal Antibody - #BF8008
(2)
Product Info
Source:
Mouse
Application:
IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Clonality:
Monoclonal [AFfirm8008]
Specificity:
SIGLEC15 Mouse Monoclonal Antibody detects endogenous levels of total SIGLEC15.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:
Fold/Unfold
CD33 antigen-like 3;CD33 molecule-like 3;CD33L3;HsT1361;Sialic acid-binding Ig-like lectin 15;SIG15_HUMAN;Siglec-15;SIGLEC15;
Immunogens
Immunogen:
A synthesized peptide derived from human SIGLEC15.
Uniprot:
Gene(ID):
Expression:
Sequence:
- Q6ZMC9 SIG15_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEKSIWLLACLAWVLPTGSFVRTKIDTTENLLNTEVHSSPAQRWSMQVPPEVSAEAGDAAVLPCTFTHPHRHYDGPLTAIWRAGEPYAGPQVFRCAAARGSELCQTALSLHGRFRLLGNPRRNDLSLRVERLALADDRRYFCRVEFAGDVHDRYESRHGVRLHVTAAPRIVNISVLPSPAHAFRALCTAEGEPPPALAWSGPALGNSLAAVRSPREGHGHLVTAELPALTHDGRYTCTAANSLGRSEASVYLFRFHGASGASTVALLLGALGFKALLLLGVLAARAARRRPEHLDTPDTPPRSQAQESNYENLSQMNPRSPPATMCSP
Research Backgrounds
Function:
Binds sialylated glycoproteins.
Subcellular Location:
Membrane>Single-pass type I membrane protein.
Tissue Specificity:
Expressed in macrophage and/or dendritic cells of spleen and lymph nodes.
Family&Domains:
Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
Restrictive clause
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For Research Use Only.
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