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1) Structure-based identification of HNF4α agonists: Rosmarinic acid as a promising candidate for NAFLD treatment.
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2) METTL3 and IGF2BP2 coordinately regulate FOSL1 mRNA via m6A modification, suppressing trophoblast invasion and contributing to fetal growth restriction.
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3) ALDH1A3 contributes to tumorigenesis in high-grade serous ovarian cancer by epigenetic modification.
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4) Autophagy Improves Inflammatory Response in Sepsis Accompanied by Changes in Gut Microbiota.
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5) Peptide BG From Bitter Gourd (Momordica Charantia) Improves Adjuvant-Induced Arthritis by Modulating the Necroptosis/Neutrophil Extracellular Traps/Inflammation Axis and the Gut Microbiota.
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6) Citrate-coated silver nanoparticles loaded with agomelatine provide neuronal therapy in acute cerebral ischemia/reperfusion of rats by inhibiting the oxidative stress, endoplasmic reticulum stress, and P2X7 receptor-mediated inflammasome.
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7) Pilocarpine mediated excessive calcium accumulation leads to ciliary muscle cell senescence and apoptosis.
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8) Exploration of the miR-187-3p/CNR2 pathway in modulating osteoblast differentiation and treating postmenopausal osteoporosis through mechanical stress.
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9) IKBKE promotes the ZEB2-mediated EMT process by phosphorylating HMGA1a in glioblastoma.
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10) Celastrol alleviates subconjunctival fibrosis induced by silicone implants mimicking glaucoma surgery.
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11) CircNCX1 modulates cardiomyocyte proliferation through promoting ubiquitination of BRG1.
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12) MEK inhibitor trametinib combined with PI3K/mTOR inhibitor BEZ-235 as an effective strategy against NSCLC through impairment of glucose metabolism.
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13) Integrative analysis of non12-hydroxylated bile acid revealed the suppressed molecular map of alternative pathway in nonalcoholic steatohepatitis mice.
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14) ZFHX2-AS1 interacts with DKC1 to regulate ARHGAP5 pseudouridylation and suppress ovarian cancer progression.
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15) Integrated bioinformatics analysis reveals that CCBP2 and GPR87 are new GPCR-associated biomarkers for preeclampsia.