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1) Aerobic Exercise Restores Hippocampal Neurogenesis and Cognitive Function by Decreasing Microglia Inflammasome Formation Through Irisin/NLRP3 Pathway.
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2) Regulation of selective class switching provides long-term therapeutic benefits for hay fever.
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3) TRPM7 Deficiency Accelerates Vascular Senescence by Inhibiting H3K18 Lactylation.
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4) Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice.
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5) Diabetes Advances Cardiomyocyte Senescence Through Interfering Rnd3 Expression and Function.
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6) Vine tea (Ampelopsis grossedentata) ameliorates chronic alcohol-induced hepatic steatosis, oxidative stress, and inflammation via YTHDF2/PGC-1α/SIRT3 axis.
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7) Aβ -induced excessive mitochondrial fission drives type H blood vessels injury to aggravate bone loss in APP/PS1 mice with Alzheimer's diseases.
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8) Reduction of DNA Topoisomerase Top2 Reprograms the Epigenetic Landscape and Extends Health and Life Span Across Species.
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9) Bacterial infection in weaned piglets promotes diarrhea by inducing the NLRP3 inflammasome-pyroptosis pathway.
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10) β-elemene promotes ferroptosis to improve the sensitivity of imatinib in gastrointestinal stromal tumours by targeting N6AMT1.
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11) Integrating single-cell and spatial transcriptomics reveals the cellular heterogeneity of vestibular schwannoma.
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12) Comprehensive single-cell RNA analysis reveals intertumoral microenvironment heterogeneity and hub niche of carcinogenesis in thyroid cancer.
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13) A nanoplatform integrating sonodynamic and manganese to enhance tumor immunotherapy via synergistic activation of the cGAS-STING pathway.
Product: 1Year: 2025Journal: Materials & DesignImpactFactor: 7.900DOI: 10.1016/j.matdes.2025.115141 -
14) Integrating bulk, single-cell, and spatial transcriptomics to identify and functionally validate novel targets to enhance immunotherapy in NSCLC.
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15) Targeting TNFAIP2 with NIR-II CRISPR-Cas9 nanosystem to overcome cisplatin resistance in laryngeal cancer.