Claudin 11 Antibody - #AF0750
| Product: | Claudin 11 Antibody |
| Catalog: | AF0750 |
| Description: | Rabbit polyclonal antibody to Claudin 11 |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| Mol.Wt.: | 20kDa; 22kD(Calculated). |
| Uniprot: | O75508 |
| RRID: | AB_2834126 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# AF0750, RRID:AB_2834126.
Fold/Unfold
Claudin 11; Claudin-11; CLD11_HUMAN; Cldn11; Oligodendrocyte transmembrane protein; Oligodendrocyte-specific protein; OSP; OTM;
Immunogens
- O75508 CLD11_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVTCGYTIPTCRKLDELGSKGLWADCVMATGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRRAQLAGVLLILLALCALVATIWFPVCAHRETTIVSFGYSLYAGWIGAVLCLVGGCVILCCAGDAQAFGENRFYYTAGSSSPTHAKSAHV
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O75508 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y191 | Phosphorylation | Uniprot | |
| Y192 | Phosphorylation | Uniprot | |
| S196 | Phosphorylation | Uniprot | |
| S197 | Phosphorylation | Uniprot | |
| S198 | Phosphorylation | Uniprot |
Research Backgrounds
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Cell junction>Tight junction. Cell membrane>Multi-pass membrane protein.
Interacts with tetraspanin-3/TSPAN3 (By similarity). Interacts with OCLN.
Belongs to the claudin family.
Research Fields
· Cellular Processes > Cellular community - eukaryotes > Tight junction. (View pathway)
· Environmental Information Processing > Signaling molecules and interaction > Cell adhesion molecules (CAMs). (View pathway)
· Human Diseases > Infectious diseases: Viral > Hepatitis C.
· Organismal Systems > Immune system > Leukocyte transendothelial migration. (View pathway)
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