Goat Anti-Rabbit IgG (H+L) HRP
Price Size
$250 50ul
$350 100ul
$450 200ul

Same day delivery


For pricing and ordering contact:

local distributors
  • Product Name
    Goat Anti-Rabbit IgG (H+L) HRP
  • Catalog No.
    S0001
  • RRID
    AB_2839429
  • Source
    Goat
  • Application
    WB,IHC
  • Reactivity
    Rabbit

Product Information

Applications:

WB 1:3000~1:10000, IHC 1:200
*The optimal dilutions should be determined by the end user.

Reactivity:

Rabbit

Source:

Goat

Clonality:

Polyclonal

Purification:

affinity purification.

RRID:

AB_2839429
Please cite this product as: Affinity Biosciences Cat# S0001, RRID:AB_2839429.

Storage Condition and Buffer:

HRP-labeled Goat IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl.

Immunogen Information in 3D

Immunogen:

The antiserum was developed in goat using the Rabbit IgG as the immunogen.

Molecular Weight:

Observed Mol.Wt.: Not available.
Predicted Mol.Wt.: Not available.

Not available

Reference Citations:

1). Lei R et al. bHLH121 Functions as A Direct Link that Facilitates the Activation of FIT by bHLH IVc Transcription Factors for Maintaining Fe Homeostasis in Arabidopsis. Mol Plant 2020 Jan 18 (PubMed: 31962167) [IF=12.084]

2). Bian WX et al. Binding of cellular nucleolin with the viral core RNA G-quadruplex structure suppresses HCV replication. Nucleic Acids Res 2018 Nov 20 (PubMed: 30462330) [IF=11.501]

Application: WB    Species:human;    Sample:hepatoma cell lines

(B) G4 pull-down and Western blot. The fourth lane represents cell lysates directly used for western blot. β-actin was used as an internal control.


3). Wu H et al. Breaking the vicious loop between inflammation, oxidative stress and coagulation, a novel anti-thrombus insight of nattokinase by inhibiting LPS-induced inflammation and oxidative stress. Redox Biol 2020 Mar 11;32:101500 (PubMed: 32193146) [IF=9.986]

4). Zhang D et al. Cold to Hot: Rational Design of Minimalist Multifunctional Photo-Immunotherapy Nanoplatform toward Boosting Immunotherapy Capability. ACS Appl Mater Interfaces 2019 Aug 20 (PubMed: 31429272) [IF=8.758]

5). Zhang J et al. Task-Specific Design of Immune-Augmented Nanoplatform to Enable High-Efficiency Tumor Immunotherapy. ACS Appl Mater Interfaces 2019 Oct 28 (PubMed: 31657540) [IF=8.758]

6). Xu X et al. Progerin accumulation in nucleus pulposus cells impairs mitochondrial function and induces intervertebral disc degeneration and therapeutic effects of sulforaphane. Theranostics 2019 Apr 12;9(8):2252-2267 (PubMed: 31149042) [IF=8.579]

7). Xie-an Yu et al. A cancer-specific activatable theranostic nanodrug for enhanced therapeutic efficacy via amplification of oxidative stress. Theranostics 2020, Vol. 10, Issue 1 [IF=8.579]

8). Zhang W;Wang Q;Xing X;Yang L;Xu M;Cao C;Wang R;Li W;Niu X;Gao D; et al. The antagonistic effects and mechanisms of microRNA‐26a action in hypertensive vascular remodelling. Br J Pharmacol 2021 Mar;178(5):1037-1054. (PubMed: 33305374) [IF=7.730]

9). Wang Y et al. The interaction of YBX1 with G3BP1 promotes renal cell carcinoma cell metastasis via YBX1/G3BP1-SPP1- NF-κB signaling axis. J Exp Clin Cancer Res 2019 Sep 3;38(1):386 (PubMed: 31481087) [IF=7.068]

10). Yang L et al. Protopanaxadiol inhibits epithelial-mesenchymal transition of hepatocellular carcinoma by targeting STAT3 pathway. Cell Death Dis 2019 Aug 20;10(9):630 (PubMed: 31431619) [IF=6.304]

11). Chen Z;Wu C;Liu Y;Li H;Zhu Y;Huang C;Lin H;Qiao Q;Huang M;Zhu Q;Wang L; et al. ELABELA attenuates deoxycorticosterone acetate/salt-induced hypertension and renal injury by inhibition of NADPH oxidase/ROS/NLRP3 inflammasome pathway. Cell Death Dis 2020 Aug 22;11(8):698. (PubMed: 32829380) [IF=6.304]

12). Zhou B;Fang L;Dong Y;Yang J;Chen X;Zhang N;Zhu Y;Huang T; et al. Mitochondrial quality control protects photoreceptors against oxidative stress in the H 2 O 2-induced models of retinal degeneration diseases. Cell Death Dis 2021 Apr 20;12(5):413. (PubMed: 33879768) [IF=6.304]

13). Li XX et al. Protective effects of acarbose against vascular endothelial dysfunction through inhibiting Nox4/NLRP3 inflammasome pathway in diabetic rats. Free Radic Biol Med 2019 Sep 18 (PubMed: 31541678) [IF=6.170]

14). Li Y et al. 2',3'-Cyclic-nucleotide 3'-phosphodiesterase contributes to epithelial-mesenchymal transition of lens epithelial cells through the notch signalling pathway. Cell Prolif 2019 Nov;52(6):e12707 (PubMed: 31617266) [IF=5.753]

15). Xiong Y et al. Hypoxia-inducible factor 1α-induced epithelial-mesenchymal transition of endometrial epithelial cells may contribute to the development of endometriosis. Hum Reprod 2016 Jun;31(6):1327-38 (PubMed: 27094478) [IF=5.733]

Application: WB    Species:human;    Sample:Not available

Figure 2 The expression of epithelial –mesenchymal transition (EMT) markers and b-catenin was detected at each time point. (A) Immunoblotting analysis of human primary cultured endometrial epithelial cell extracts using the corresponding antibodies. The ratios of each protein relative to non-treated cells were normalized to GAPDH. (B) The relative expression of HIF-1a, N-cadherin, E-cadherin, b-catenin, vimentin and snail proteins in human endometrial epithelial glands under hypoxic conditions at each time point was investigated by western blot. Data are represented as mean+SD and are representative of the relative expression of protein normalized by GAPDH. All experiments were repeated four times. Data were evaluated by one-way ANOVA analysis (*P , 0.05, **P , 0.01 compared with untreated group). (C) The changed cellular morphologies of human endometrial epithelial glands in hypoxia compared with cells in normoxia, the hypoxic time was 48 h. Red arrows indicate the spindle-shaped and fibroblast-like cells.


16). Fan X;Li J;Deng X;Lu Y;Feng Y;Ma S;Wen H;Zhao Q;Tan W;Shi T;Wang Z; et al. Design, synthesis and bioactivity study of N-salicyloyl tryptamine derivatives as multifunctional agents for the treatment of neuroinflammation. Eur J Med Chem 2020 May 1;193:112217. (PubMed: 32182488) [IF=5.572]

17). Ma S;Zhu L;Fan X;Luo T;Liu D;Liang Z;Hu X;Shi T;Tan W;Wang Z; et al. Melatonin derivatives combat with inflammation-related cancer by targeting the Main Culprit STAT3. Eur J Med Chem 2021 Feb 5;211:113027. (PubMed: 33248852) [IF=5.572]

18). Jiang Y et al. Hedgehog pathway inhibition causes primary follicle atresia and decreases female germline stem cell proliferation capacity or stemness. Stem Cell Res Ther 2019 Jul 5;10(1):198 (PubMed: 31277696) [IF=5.116]

19). Chen T et al. Epstein-Barr virus tegument protein BGLF2 inhibits NF-κB activity by preventing p65 Ser536 phosphorylation. FASEB J 2019 Jul 23:fj201901196RR (PubMed: 31337264) [IF=4.966]

20). Liu N;Sun Q;Xu H;Yu X;Chen W;Wei H;Jiang J;Xu Y;Lu W; et al. Hyperuricemia induces lipid disturbances mediated by LPCAT3 upregulation in the liver. FASEB J 2020 Aug 11. (PubMed: 32780898) [IF=4.966]

21). Jia Y;Zhang D;Li H;Luo S;Xiao Y;Han L;Zhou F;Wang C;Feng L;Wang G;Wu P;Xiao C;Yu H;Du J;Bao H; et al. Activation of FXR by Ganoderic Acid A Promotes Remyelination in Multiple Sclerosis via Anti-inflammation and Regeneration Mechanism. Biochem Pharmacol 2021 Jan 19;114422. (PubMed: 33482151) [IF=4.960]

22). Ding S et al. Resveratrol alleviates chronic "real-world" ambient particulate matter-induced lung inflammation and fibrosis by inhibiting NLRP3 inflammasome activation in mice. Ecotoxicol Environ Saf 2019 Oct 30;182:109425 (PubMed: 31295660) [IF=4.872]

23). Zhang Y et al. Blockage of ROS-ERK-DLP1 signaling and mitochondrial fission alleviates Cr(VI)-induced mitochondrial dysfunction in L02 hepatocytes. Ecotoxicol Environ Saf 2019 Oct 14;186:109749 (PubMed: 31622878) [IF=4.872]

24). Zhang Y et al. Blockage of ROS-ERK-DLP1 signaling and mitochondrial fission alleviates Cr(VI)-induced mitochondrial dysfunction in L02 hepatocytes. Ecotoxicol Environ Saf 2019 Oct 14;186:109749 (PubMed: 31622878) [IF=4.872]

25). Ma Y;Liang Y;Liang N;Zhang Y;Xiao F; et al. Identification and functional analysis of senescence-associated secretory phenotype of premature senescent hepatocytes induced by hexavalent chromium. Ecotoxicol Environ Saf 2021 Jan 10;211:111908. (PubMed: 33440265) [IF=4.872]

26). Luo DD et al. Tetrahydrocurcumin and octahydrocurcumin, the primary and final hydrogenated metabolites of curcumin, possess superior hepatic-protective effect against acetaminophen-induced liver injury: Role of CYP2E1 and Keap1-Nrf2 pathway. Food Chem Toxicol 2019 Jan;123:349-362 (PubMed: 30423402) [IF=4.679]

27). Hu R;Wang MQ;Liu LY;You HY;Wu XH;Liu YY;Wang YJ;Lu L;Xiao W;Wei LB; et al. Calycosin inhibited autophagy and oxidative stress in chronic kidney disease skeletal muscle atrophy by regulating AMPK/SKP2/CARM1 signalling pathway. J Cell Mol Med 2020 Oct;24(19):11084-11099. (PubMed: 32910538) [IF=4.658]

28). Tao J;Yang P;Xie L;Pu Y;Guo J;Jiao J;Sun L;Lu D; et al. Gastrodin induces lysosomal biogenesis and autophagy to prevent the formation of foam cells via AMPK‐FoxO1‐TFEB signalling axis. J Cell Mol Med 2021 May 10. (PubMed: 33973365) [IF=4.658]

29). Jiang Y et al. Resveratrol Plays a Protective Role against Premature Ovarian Failure and Prompts Female Germline Stem Cell Survival. Int J Mol Sci 2019 Jul 23;20(14) (PubMed: 31340581) [IF=4.556]

30). Meng X;Zhang J;Wu H;Yu D;Fang X; et al. Akkermansia muciniphila Aspartic Protease Amuc_1434* Inhibits Human Colorectal Cancer LS174T Cell Viability via TRAIL-Mediated Apoptosis Pathway. Int J Mol Sci 2020 May 11;21(9):E3385. (PubMed: 32403433) [IF=4.556]

31). Meng X et al. A Purified Aspartic Protease from Akkermansia Muciniphila Plays an Important Role in Degrading Muc2. Int J Mol Sci 2019 Dec 20;21(1) (PubMed: 31861919) [IF=4.556]

32). Zeng SY et al. Nox1/4 dual inhibitor GKT137831 attenuates hypertensive cardiac remodelling associating with the inhibition of ADAM17-dependent proinflammatory cytokines-induced signalling pathways in the rats with abdominal artery constriction. Biomed Pharmacother 2019 Jan;109:1907-1914 (PubMed: 30551445) [IF=4.545]

33). Duan S et al. Effect of vitexin on alleviating liver inflammation in a dextran sulfate sodium (DSS)-induced colitis model. Biomed Pharmacother 2020 Jan;121:109683 (PubMed: 31810123) [IF=4.545]

34). Zhong L;Zhang H;Ding ZF;Li J;Lv JW;Pan ZJ;Xu DX;Yin ZS; et al. Erythropoietin-Induced Autophagy Protects Against Spinal Cord Injury and Improves Neurological Function via the Extracellular-Regulated Protein Kinase Signaling Pathway. Mol Neurobiol 2020 Jul 9. (PubMed: 32647973) [IF=4.500]

35). Liu H et al. Long non-coding RNA MALAT1 mediates hypoxia-induced pro-survival autophagy of endometrial stromal cells in endometriosis. J Cell Mol Med 2019 Jan;23(1):439-452 (PubMed: 30324652) [IF=4.486]

36). Zeng SY et al. Rutaecarpine prevents hypertensive cardiac hypertrophy involving the inhibition of Nox4-ROS-ADAM17 pathway. J Cell Mol Med 2019 Apr 5 (PubMed: 30953402) [IF=4.486]

37). Hu R;Wang MQ;Liu LY;You HY;Wu XH;Liu YY;Wang YJ;Lu L;Xiao W;Wei LB; et al. Calycosin inhibited autophagy and oxidative stress in chronic kidney disease skeletal muscle atrophy by regulating AMPK/SKP2/CARM1 signalling pathway. J Cell Mol Med 2020 Oct;24(19):11084-11099. (PubMed: 32910538) [IF=4.486]

38). Tao J;Yang P;Xie L;Pu Y;Guo J;Jiao J;Sun L;Lu D; et al. Gastrodin induces lysosomal biogenesis and autophagy to prevent the formation of foam cells via AMPK‐FoxO1‐TFEB signalling axis. J Cell Mol Med 2021 May 10. (PubMed: 33973365) [IF=4.486]

39). Xiao H;Chen H;Jiang R;Zhang L;Wang L;Gan H;Jiang N;Zhao J;Zhai X;Liang P; et al. NLRP6 contributes to inflammation and brain injury following intracerebral haemorrhage by activating autophagy. J Mol Med (Berl) 2020 Aug 12. (PubMed: 32783081) [IF=4.427]

40). Xie X et al. Advanced glycation end products reduce macrophage-mediated killing of Staphylococcus aureus by ARL8 upregulation and inhibition of autolysosome formation. Eur J Immunol 2020 Apr 6 (PubMed: 32250445) [IF=4.404]

41). An X et al. Increasing the TRPM2 Channel Expression in Human Neuroblastoma SH-SY5Y Cells Augments the Susceptibility to ROS-Induced Cell Death. Cells 2019 Jan 8;8(1) (PubMed: 30625984) [IF=4.366]

42). Li CL et al. Comparison of anti-inflammatory effects of berberine, and its natural oxidative and reduced derivatives from Rhizoma Coptidis in vitro and in vivo. Phytomedicine 2019 Jan;52:272-283 (PubMed: 30599908) [IF=4.268]

43). Fan H et al. The in vitro and in vivo anti-inflammatory effect of osthole, the major natural coumarin from Cnidium monnieri (L.) Cuss, via the blocking of the activation of the NF-κB and MAPK/p38 pathways. Phytomedicine 2019 Feb 18;58:152864 (PubMed: 30878874) [IF=4.268]

44). Gu K et al. TAZ promotes the proliferation and osteogenic differentiation of human periodontal ligament stem cells via the p-SMAD3. J Cell Biochem 2019 Sep 3 (PubMed: 31478222) [IF=4.237]

45). Yin X et al. The Nuclear-Localized RxLR Effector PvAvh74 From Plasmopara viticola Induces Cell Death and Immunity Responses in Nicotiana benthamiana. Front Microbiol 2019 Jul 10;10:1531 (PubMed: 31354650) [IF=4.235]

46). Wu X et al. Protective Effect of Patchouli Alcohol Against High-Fat Diet Induced Hepatic Steatosis by Alleviating Endoplasmic Reticulum Stress and Regulating VLDL Metabolism in Rats. Front Pharmacol 2019 Oct 1;10:1134 (PubMed: 31632274) [IF=4.225]

47). Xu Y;Guo X;Wang G;Zhou C; et al. Vitamin C Inhibits Metastasis of Peritoneal Tumors By Preventing Spheroid Formation in ID8 Murine Epithelial Peritoneal Cancer Model. Front Pharmacol 2020 May 12;11:645. (PubMed: 32477126) [IF=4.225]

48). Lin Y;Zheng X;Chen J;Luo D;Xie J;Su Z;Huang X;Yi X;Wei L;Cai J;Sun Z; et al. Protective Effect of Bruguiera gymnorrhiza (L.) Lam. Fruit on Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice: Role of Keap1/Nrf2 Pathway and Gut Microbiota. Front Pharmacol 2020 Feb 3;10:1602. (PubMed: 32116661) [IF=4.225]

49). Gu Y;Zhang Y;Li M;Huang Z;Jiang J;Chen Y;Chen J;Jia Y;Zhang L;Zhou F; et al. Ferulic acid ameliorates atherosclerotic injury by modulating gut microbiota and lipid metabolism. Front Pharmacol 2021 Mar 25;12:621339. (PubMed: 33841148) [IF=4.225]

50). Yang Y et al. Black Sesame Seeds Ethanol Extract Ameliorates Hepatic Lipid Accumulation, Oxidative Stress, and Insulin Resistance in Fructose-Induced Nonalcoholic Fatty Liver Disease. J Agric Food Chem 2018 Oct 10;66(40):10458-10469 (PubMed: 30244573) [IF=4.192]

51). Chai Z et al. PADI3 plays an antitumor role via the Hsp90/CKS1 pathway in colon cancer. Cancer Cell Int 2019 Nov 5;19:277 (PubMed: 31708688) [IF=4.175]

52). Zhu M;Wang Y;Wang F;Li L;Qiu X; et al. CircFBXL5 promotes the 5-FU resistance of breast cancer via modulating miR-216b/HMGA2 axis. Cancer Cell Int 2021 Jul 19;21(1):384. (PubMed: 34281530) [IF=4.175]

53). Li X;Lu Z;Zhou F;Jin W;Yang Y;Chen S;Xie Z;Zhao Y; et al. Indoxyl sulfate promotes the atherosclerosis through up-regulating the miR-34a expression in endothelial cells and vascular smooth muscle cells in vitro. Vascul Pharmacol 2020 Jun 25;106763. (PubMed: 32593718) [IF=4.152]

54). Seo E et al. Exendin-4 in combination with adipose-derived stem cells promotes angiogenesis and improves diabetic wound healing. J Transl Med 2017 Feb 15;15(1):35 (PubMed: 28202074) [IF=4.124]

55). Yuan CH et al. Secreted Rv1768 From RD14 of Mycobacterium tuberculosis Activates Macrophages and Induces a Strong IFN-γ-Releasing of CD4+ T Cells. Front Cell Infect Microbiol 2019 Oct 14;9:341 (PubMed: 31681622) [IF=4.123]

56). Xin X et al. The suppressive role of calcium sensing receptor in endometrial cancer. Sci Rep 2018 Jan 18;8(1):1076 (PubMed: 29348629) [IF=3.998]

57). Tan L et al. Dihydroberberine, a hydrogenated derivative of berberine firstly identified in Phellodendri Chinese Cortex, exerts anti-inflammatory effect via dual modulation of NF-κB and MAPK signaling pathways. Int Immunopharmacol 2019 Aug 8;75:105802 (PubMed: 31401380) [IF=3.943]

58). Jia Y et al. Cordycepin (3\'-deoxyadenosine) promotes remyelination via suppression of neuroinflammation in a cuprizone-induced mouse model of demyelination. Int Immunopharmacol 2019 Oct;75:105777 (PubMed: 31357085) [IF=3.943]

59). Liu S et al. Isosteroid alkaloids with different chemical structures from Fritillariae cirrhosae bulbus alleviate LPS-induced inflammatory response in RAW 264.7 cells by MAPK signaling pathway. Int Immunopharmacol 2019 Dec 6;78:106047 (PubMed: 31816576) [IF=3.943]

60). Wei X;Sun C;Zhou RP;Ma GG;Yang Y;Lu C;Hu W; et al. Nerve growth factor promotes ASIC1a expression via the NF-κB pathway and enhances acid-induced chondrocyte apoptosis. Int Immunopharmacol 2020 Mar 5;82:106340. (PubMed: 32146316) [IF=3.943]

61). Wang X;Yin H;Fan L;Zhou Y;Tang X;Fei X;Tang H;Peng J;Zhang J;Xue Y;Luo J;Jin Q;Jin Q; et al. Shionone alleviates NLRP3 inflammasome mediated pyroptosis in interstitial cystitis injury. Int Immunopharmacol 2020 Nov 19;107132. (PubMed: 33223465) [IF=3.943]

62). Nan C et al. Tetramethylpyrazine induces differentiation of human umbilical cord-derived mesenchymal stem cells into neuron-like cells in vitro. Int J Oncol 2016 Jun;48(6):2287-94 (PubMed: 27035275) [IF=3.899]

63). Li C;Liu J;Zhang Q;Cui K;Ge Q;Wang C;Chen Z; et al. Upregulation of E‑cadherin expression mediated by a novel dsRNA suppresses the growth and metastasis of bladder cancer cells by inhibiting β-catenin/TCF target genes. Int J Oncol 2018 Jun;52(6):1815-1826. (PubMed: 29620261) [IF=3.899]

64). Li H et al. MicroRNA-181a regulates epithelial-mesenchymal transition by targeting PTEN in drug-resistant lung adenocarcinoma cells. Int J Oncol 2015 Oct;47(4):1379-92 (PubMed: 26323677) [IF=3.899]

65). Wang M et al. Long Non-Coding RNA MEG3 Promotes Apoptosis of Vascular Cells and is Associated with Poor Prognosis in Ischemic Stroke. J Atheroscler Thromb 2019 Oct 25 (PubMed: 31656272) [IF=3.876]

66). Ding CL et al. Identification of retinoid acid induced 16 as a novel androgen receptor target in prostate cancer cells. Mol Cell Endocrinol 2020 Jan 31:110745 (PubMed: 32014455) [IF=3.871]

67). Guo L et al. Resveratrol Induces Differentiation of Human Umbilical Cord Mesenchymal Stem Cells into Neuron-Like Cells. Stem Cells Int 2017;2017:1651325 (PubMed: 28512471) [IF=3.869]

68). Shi Y et al. Synaptic Plasticity of Human Umbilical Cord Mesenchymal Stem Cell Differentiating into Neuron-like Cells In Vitro Induced by Edaravone. Stem Cells Int 2018 Oct 28;2018:5304279 (PubMed: 30510585) [IF=3.869]

69). Chen W et al. Functions of duplicated glucosinolate sulfatases in the development and host adaptation of Plutella xylostella. Insect Biochem Mol Biol 2020 Apr;119:103316 (PubMed: 31953191) [IF=3.827]

70). Liu C et al. PADI4 stimulates esophageal squamous cell carcinoma tumor growth and up-regulates CA9 expression. Mol Carcinog 2018 Sep 22 (PubMed: 30242913) [IF=3.825]

71). Zeng SY et al. Evidence That ADAM17 Mediates the Protective Action of CGRP against Angiotensin II-Induced Inflammation in Vascular Smooth Muscle Cells. Mediators Inflamm 2018 Jun 12;2018:2109352 (PubMed: 30046277) [IF=3.758]

72). Liu Y;Huang J;Yu N;Wei S;Liu Z; et al. Involvement of WNT2 in trophoblast cell behavior in preeclampsia development. Cell Cycle 2020 Aug 11;1-9. (PubMed: 32779546) [IF=3.699]

73). Huang S et al. Nepeta angustifolia attenuates responses to vascular inflammation in high glucose-induced human umbilical vein endothelial cells through heme oxygenase-1 induction. J Ethnopharmacol 2019 Mar 1;231:187-196 (PubMed: 30419276) [IF=3.690]

74). Chen JF et al. Aqueous extract of Bruguiera gymnorrhiza leaves protects against dextran sulfate sodium induced ulcerative colitis in mice via suppressing NF-κB activation and modulating intestinal microbiota. J Ethnopharmacol 2020 Jan 7:112554 (PubMed: 31923541) [IF=3.690]

75). Yang Q et al. Yinning Tablet, a hospitalized preparation of Chinese herbal formula for hyperthyroidism, ameliorates thyroid hormone-induced liver injury in rats: Regulation of mitochondria-mediated apoptotic signals. J Ethnopharmacol 2020 Apr 24;252:112602 (PubMed: 32004632) [IF=3.690]

76). Zhang Y;Gu Y;Chen Y;Huang Z;Li M;Jiang W;Chen J;Rao W;Luo S;Chen Y;Chen J;Li L;Jia Y;Liu M;Zhou F; et al. Dingxin Recipe IV attenuates atherosclerosis by regulating lipid metabolism through LXR-α/SREBP1 pathway and modulating the gut microbiota in ApoE-/- mice fed with HFD. J Ethnopharmacol 2020 Oct 1;266:113436. (PubMed: 33011372) [IF=3.690]

77). Wang L;Gu J;Zong M;Zhang Q;Li H;Li D;Mou X;Liu P;Liu Y;Qiu F;Zhao F; et al. Anti-inflammatory action of physalin A by blocking the activation of NF-κB signaling pathway. J Ethnopharmacol 2020 Oct 19;113490. (PubMed: 33091501) [IF=3.690]

78). Zhong W et al. Adipose specific aptamer adipo-8 recognizes and interacts with APMAP to ameliorates fat deposition in vitro and in vivo. Life Sci 2020 Jun 15;251:117609 (PubMed: 32272180) [IF=3.647]

79). Chen J;Yang Y;Lv Z;Shu A;Du Q;Wang W;Chen Y;Xu H; et al. Study on the inhibitive effect of Catalpol on diabetic nephropathy. Life Sci 2020 Sep 15;257:118120. (PubMed: 32693244) [IF=3.647]

80). Zhao J et al. Dehydroepiandrosterone alleviates E. Coli O157:H7-induced inflammation by preventing the activation of p38 MAPK and NF-κB pathways in mice peritoneal macrophages. Mol Immunol 2019 Jul 24;114:114-122 (PubMed: 31351412) [IF=3.641]

81). Zhao ZH et al. PirB Overexpression Exacerbates Neuronal Apoptosis by Inhibiting TrkB and mTOR Phosphorylation After Oxygen and Glucose Deprivation Injury. Cell Mol Neurobiol 2017 May;37(4):707-715 (PubMed: 27443384) [IF=3.606]

82). Liu X;Qiu Y;Liu Y;Huang N;Hua C;Wang Q;Wu Z;Lu J;Song P;Xu J;Li P;Yin Y; et al. Citronellal ameliorates doxorubicin‐induced hepatotoxicity via antioxidative stress, antiapoptosis, and proangiogenesis in rats. J Biochem Mol Toxicol 2021 Feb;35(2):e22639. (PubMed: 33051984) [IF=3.606]

83). Chen Z et al. Lower Expression of Gelsolin in Colon Cancer and Its Diagnostic Value in Colon Cancer Patients. J Cancer 2019 Jan 30;10(5):1288-1296 (PubMed: 30854138) [IF=3.565]

84). Sun Y;Li S;Yu W;Chen C;Liu T;Li L;Zhang D;Zhao Z;Gao J;Wang X;Shi D;Liu L; et al. CD148 Serves as a Prognostic Marker of Gastric Cancer and Hinders Tumor Progression by Dephosphorylating EGFR. J Cancer 2020 Feb 19;11(9):2667-2678. (PubMed: 32201537) [IF=3.565]

85). Wang DD;Li Y;Wu YJ;Wu YL;Han J;Olatunji OJ;Wang L;Zuo J; et al. Xanthones from securidaca inappendiculata antagonized the anti-rheumatic effects of methotrexate in vivo by promoting its secretion into urine. Expert Opin Drug Metab Toxicol 2020 Nov 12;1-10. (PubMed: 33107357) [IF=3.470]

86). Cui X et al. IL22 furthers malignant transformation of rat mesenchymal stem cells, possibly in association with IL22RA1/STAT3 signaling. Oncol Rep 2019 Apr;41(4):2148-2158 (PubMed: 30816520) [IF=3.417]

87). Cui X et al. IL22 furthers malignant transformation of rat mesenchymal stem cells, possibly in association with IL22RA1/STAT3 signaling. Oncol Rep 2019 Apr;41(4):2148-2158 (PubMed: 30816520) [IF=3.417]

88). Zhang T et al. Interaction with tumor‑associated macrophages promotes PRL‑3‑induced invasion of colorectal cancer cells via MAPK pathway‑induced EMT and NF‑κB signaling‑induced angiogenesis. Oncol Rep 2019 Mar 7 (PubMed: 30864736) [IF=3.417]

89). Sun X et al. (‑)‑Epigallocatechin‑3‑gallate inhibits bladder cancer stem cells via suppression of sonic hedgehog pathway. Oncol Rep 2019 Jul;42(1):425-435 (PubMed: 31180522) [IF=3.417]

90). An Q;Liu T;Wang MY;Yang YJ;Zhang ZD;Liu ZJ;Yang B; et al. KRT7 promotes epithelial‑mesenchymal transition in ovarian cancer via the TGF‑β/Smad2/3 signaling pathway. Oncol Rep 2020 Dec 8;45(2):481-492. (PubMed: 33416175) [IF=3.417]

91). Luan D et al. MST4 modulates the neuro-inflammatory response by regulating IκBα signaling pathway and affects the early outcome of experimental ischemic stroke in mice. Brain Res Bull 2019 Nov 10 (PubMed: 31722252) [IF=3.370]

92). He J;Mao Y;Huang W;Li M;Zhang H;Qing Y;Lu S;Xiao H;Li K; et al. Methylcrotonoyl-CoA Carboxylase 2 Promotes Proliferation, Migration and Invasion and Inhibits Apoptosis of Prostate Cancer Cells Through Regulating GLUD1-P38 MAPK Signaling Pathway. Onco Targets Ther 2020 Jul 28;13:7317-7327. (PubMed: 32801758) [IF=3.337]

93). Ma G;Li G;Gou A;Xiao Z;Xu Y;Song S;Guo K;Liu Z; et al. Long non-coding RNA ELFN1-AS1 in the pathogenesis of pancreatic cancer. Ann Transl Med 2021 May;9(10):877. (PubMed: 34164511) [IF=3.297]

94). Shen YH et al. Ethyl Rosmarinate Protects High Glucose-Induced Injury in Human Endothelial Cells. Molecules 2018 Dec 19;23(12) (PubMed: 30572638) [IF=3.267]

95). Lu K;Zhou J;Deng J;Li Y;Wu C;Bao J; et al. Periplaneta americana Oligosaccharides Exert Anti-Inflammatory Activity through Immunoregulation and Modulation of Gut Microbiota in Acute Colitis Mice Model. Molecules 2021 Mar 19;26(6):1718. (PubMed: 33808686) [IF=3.267]

96). He S et al. Triptolide inhibits PDGF-induced proliferation of ASMCs through G0/G1 cell cycle arrest and suppression of the AKT/NF-κB/cyclinD1 signaling pathway. Eur J Pharmacol 2019 Nov 19:172811 (PubMed: 31756335) [IF=3.263]

97). Zhang M et al. Chronic inflammation promotes proliferation in the prostatic stroma in rats with experimental autoimmune prostatitis: study for a novel method of inducing benign prostatic hyperplasia in a rat model. World J Urol 2020 Jan 21 (PubMed: 31965289) [IF=3.217]

98). Liu Y et al. (3R, 7R)-7-Acetoxyl-9-Oxo-de-O-Methyllasiodiplodin, a Secondary Metabolite of Penicillium Sp., Inhibits LPS-Mediated Inflammation in RAW 264.7 Macrophages through Blocking ERK/MAPKs and NF-κB Signaling Pathways. Inflammation 2019 Apr 23 (PubMed: 31011928) [IF=3.212]

99). Yang K et al. Metabolomics Analysis Reveals Therapeutic Effects of α-Mangostin on Collagen-Induced Arthritis in Rats by Down-regulating Nicotinamide Phosphoribosyltransferase. Inflammation 2019 Apr;42(2):741-753 (PubMed: 30484004) [IF=3.212]

100). Wang Y;Huang H;Zeng M;Quan RP;Yang JT;Guo D;Sun Y;Deng H;Xiao H; et al. Mutation of rat Zp2 causes ROS-mediated oocyte apoptosis. Reproduction 2020 Jun 1;REP-20-0037.R2. (PubMed: 32520719) [IF=3.206]

101). Wei Y;Bai S;Yao Y;Hou W;Zhu J;Fang H;Du Y;He W;Shen B;Du J; et al. Orai–vascular endothelial-cadherin signaling complex regulates high-glucose exposure-induced increased permeability of mouse aortic endothelial cells. BMJ Open Diabetes Res Care 2021 Apr;9(1):e002085. (PubMed: 33888544) [IF=3.183]

102). Liu X et al. The role of Delta-like 4 ligand/Notch-ephrin-B2 cascade in the pathogenesis of preeclampsia by regulating functions of endothelial progenitor cell. Placenta 2015 Sep;36(9):1002-10 (PubMed: 26212082) [IF=3.177]

103). Jiang M;Lash GE;Zeng S;Liu F;Han M;Long Y;Cai M;Hou H;Ning F;Hu Y;Yang H; et al. Differential expression of serum proteins before 20 weeks gestation in women with hypertensive disorders of pregnancy: A potential role for SH3BGRL3. Placenta 2020 Nov 14;104:20-30. (PubMed: 33217630) [IF=3.177]

104). Sun L et al. Effects of high-intensity interval training on adipose tissue lipolysis, inflammation, and metabolomics in aged rats. Pflugers Arch 2020 Feb;472(2):245-258 (PubMed: 32006095) [IF=3.158]

105). Shen M et al. Xanthatin inhibits corneal neovascularization by inhibiting the VEGFR2‑mediated STAT3/PI3K/Akt signaling pathway. Int J Mol Med 2018 Aug;42(2):769-778 (PubMed: 29717775) [IF=3.098]

106). Li A et al. Epigallocatechin-3-gallate affects the proliferation, apoptosis, migration and invasion of tongue squamous cell carcinoma through the hippo-TAZ signaling pathway. Int J Mol Med 2018 Aug 9 (PubMed: 30106116) [IF=3.098]

107). Cheng Y et al. Strontium promotes osteogenic differentiation by activating autophagy via the the AMPK/mTOR signaling pathway in MC3T3‑E1 cells. Int J Mol Med 2019 Aug;44(2):652-660 (PubMed: 31173178) [IF=3.098]

108). Cheng Y et al. Strontium promotes osteogenic differentiation by activating autophagy via the the AMPK/mTOR signaling pathway in MC3T3‑E1 cells. Int J Mol Med 2019 Aug;44(2):652-660 (PubMed: 31173178) [IF=3.098]

109). Bai Z et al. Anti-atherosclerosis effect of H2S donors based on nicotinic acid and chlorfibrate structures. Bioorg Med Chem 2019 Aug 1;27(15):3307-3318 (PubMed: 31204228) [IF=3.073]

110). Bai Z et al. Anti-atherosclerosis effect of H2S donors based on nicotinic acid and chlorfibrate structures. Bioorg Med Chem 2019 Aug 1;27(15):3307-3318 (PubMed: 31204228) [IF=3.073]

111). Wang X;Li Y;Fan GF;Zhang TY;Sun B;Fan PS; et al. Effect of verapamil in the reversal of doxorubicin chemotherapy resistance in advanced gastric cancer. Eur Rev Med Pharmacol Sci 2020 Jul;24(14):7753-7763. (PubMed: 32744702) [IF=3.024]

112). Xin Y et al. Versatile Pt NCs-based chemotherapeutic agents significantly induce the apoptosis of cisplatin-resistant non-small cell lung cancer. Biochem Biophys Res Commun 2019 Apr 30;512(2):218-223 (PubMed: 30885437)

113). Lei X et al. Effects of cyclic fluid stress at different frequencies on behaviors of cells incubated on titanium alloy. Biochem Biophys Res Commun 2020 Jan 29;522(1):100-106 (PubMed: 31740003)

114). Gu C;Lu H;Qian Z; et al. Matrine reduces the secretion of exosomal circSLC7A6 from cancer-associated fibroblast to inhibit tumorigenesis of colorectal cancer by regulating CXCR5. Biochem Biophys Res Commun 2020 Jun 30;527(3):638-645. (PubMed: 32423804)

115). Luo Q;Zhang W;Liu X;Zheng Y;Gao H;Zhao Y;Zou L; et al. Delta-Like 4-Notch signaling regulates trophoblast migration and invasion by targeting EphrinB2. Biochem Biophys Res Commun 2020 Jul 5;527(4):915-921. (PubMed: 32430173)

116). Shao Q et al. MicroRNA-139-5p affects cisplatin sensitivity in human nasopharyngeal carcinoma cells by regulating the epithelial-to-mesenchymal transition. Gene 2018 Apr 30;652:48-58 (PubMed: 29427737)

117). Bao H et al. Lentinan produces a robust antidepressant-like effect via enhancing the prefrontal Dectin-1/AMPA receptor signaling pathway. Behav Brain Res 2017 Jan 15;317:263-271 (PubMed: 27693847)

118). Yu S et al. Exploring the 'cold/hot' properties of traditional Chinese medicine by cell temperature measurement. Pharm Biol 2020 Dec;58(1):208-218 (PubMed: 32114881)

119). Wei SJ;Zhang Q;Xiang YJ;Peng LY;Peng W;Ren Q;Gao YX; et al. Guizhi-Shaoyao-Zhimu decoction attenuates bone erosion in rats that have collagen-induced arthritis via modulating NF‐κB signalling to suppress osteoclastogenesis. Pharm Biol 2021 Dec;59(1):262-274. (PubMed: 33626293)

120). Chi S et al. Knockdown of long non-coding HOTAIR enhances the sensitivity to progesterone in endometrial cancer by epigenetic regulation of progesterone receptor isoform B. Cancer Chemother Pharmacol 2019 Feb;83(2):277-287 (PubMed: 30443761)

121). Zeng SY et al. A Reduction in ADAM17 Expression Is Involved in the Protective Effect of the PPAR-α Activator Fenofibrate on Pressure Overload-Induced Cardiac Hypertrophy. PPAR Res 2018 Jul 19;2018:7916953 (PubMed: 30105051)

122). Qu Y et al. 12-lipoxygenase promotes tumor progress by TGF-β1-mediated epithelial to mesenchymal transition and predicts poor prognosis in esophageal squamous cell carcinoma. Cancer Manag Res 2019 Sep 11;11:8303-8313 (PubMed: 31571988)

123). Zhu C et al. Downregulation of Proline Hydroxylase 2 and Upregulation of Hypoxia-Inducible Factor 1α are Associated with Endometrial Cancer Aggressiveness. Cancer Manag Res 2019 Nov 22;11:9907-9912 (PubMed: 31819628)

124). Song J et al. Protective effect of Berberine on reproductive function and spermatogenesis in diabetic rats via inhibition of ROS/JAK2/NFκB pathway. Andrology 2020 Feb 3 (PubMed: 32012485)

125). Ding L et al. The protective effects of polysaccharide extract from Xin-Ji-Er-Kang formula on Ang II-induced HUVECs injury, L-NAME-induced hypertension and cardiovascular remodeling in mice. BMC Complement Altern Med 2019 Jun 13;19(1):127 (PubMed: 31196042)

126). Tao H et al. LncRNA MEG3 inhibits trophoblast invasion and trophoblast-mediated VSMC loss in uterine spiral artery remodeling. Mol Reprod Dev 2019 May 8 (PubMed: 31066488)

127). Ding S et al. Combined effects of ambient particulate matter exposure and a high-fat diet on oxidative stress and steatohepatitis in mice. PLoS One 2019 Mar 28;14(3):e0214680 (PubMed: 30921449)

128). Guan SY et al. Anxiolytic effects of polydatin through the blockade of neuroinflammation in a chronic pain mouse model. Mol Pain 2020 Jan-Dec;16:1744806919900717 (PubMed: 31964240)

129). Ge QD et al. Differential Expression of miRNAs in the Hippocampi of Offspring Rats Exposed to Fluorine Combined with Aluminum during the Embryonic Stage and into Adulthood. Biol Trace Elem Res 2018 Jul 22 (PubMed: 30033483)

130). Zhu L et al. Transcription factorIRX5 promotes hepatocellular carcinoma proliferation and inhibits apoptosis by regulating the p53 signalling pathway. Cell Biochem Funct 2020 Mar 9 (PubMed: 32153043)

131). Liu S et al. Isosteroid alkaloids from Fritillaria cirrhosa bulbus as inhibitors of cigarette smoke-induced oxidative stress. Fitoterapia 2020 Jan;140:104434 (PubMed: 31760067)

132). Wang Y et al. The Role of YB1 in Renal Cell Carcinoma Cell Adhesion. Int J Med Sci 2018 Aug 6;15(12):1304-1311 (PubMed: 30275756)

133). Zhong W et al. Long non-coding RNA MIAT promotes epithelial-mesenchymal transition and is an independent risk factor for poor prognosis of tongue squamous cell carcinoma. J Oral Pathol Med 2019 Jun 5 (PubMed: 31166624)

134). Qian SQ et al. Vacuum therapy prevents corporeal veno-occlusive dysfunction and penile shrinkage in a cavernosal nerve injured rat model. Asian J Androl 2019 Jun 25 (PubMed: 31249269)

135). Wu CJ;Fu FD;Qin F;Ma M;Li T;Wei SZ;Yu BT;Yang XZ;Yuan JH; et al. Vacuum therapy ameliorates erectile dysfunction in bilateral cavernous nerve crush rats by inhibiting apoptosis and activating autophagy. Asian J Androl May-Jun 2021;23(3):273-280. (PubMed: 33473012)

136). Ding S et al. Resveratrol reduces the inflammatory response in adipose tissue and improves adipose insulin signaling in high-fat diet-fed mice. PeerJ 2018 Jun 29;6:e5173 (PubMed: 29967759)

137). Jia D et al. A novel berberine-metformin hybrid compound exerts therapeutic effects on obese type 2 diabetic rats. Clin Exp Pharmacol Physiol 2019 Jun;46(6):533-544 (PubMed: 30883863)

138). Wu K et al. Antitumor effect of ginsenoside Rg3 on gallbladder cancer by inducing endoplasmic reticulum stress-mediated apoptosis in vitro and in vivo. Oncol Lett 2018 Nov;16(5):5687-5696 (PubMed: 30344724)

139). Li J et al. Rapamycin enhanced the antitumor effects of doxorubicin in myelogenous leukemia K562 cells by downregulating the mTOR/p70S6K pathway. Oncol Lett 2019 Sep;18(3):2694-2703 (PubMed: 31404320)

140). Li H;Wang X;Tang J;Zhao H;Duan M; et al. Decreased expression levels of ELOVL6 indicate poor prognosis in hepatocellular carcinoma. Oncol Lett 2019 Dec;18(6):6214-6220. (PubMed: 31788097)

141). Liu W;Li J;Zhang D;Chen B;Wang X;Zhang X;Xue L; et al. Trefoil factor 1 and gastrokine 2 inhibit Helicobacter pylori‑induced proliferation and inflammation in gastric cardia and distal carcinogenesis. Oncol Lett 2020 Dec;20(6):318. (PubMed: 33133254)

142). Chen J;Xia Y;Peng Y;Wu S;Liu W;Zhang H;Wang T;Yang Z;Zhao S;Zhao L; et al. Analysis of the association between KIN17 expression and the clinical features/prognosis of epithelial ovarian cancer, and the effects of KIN17 in SKOV3 cells. Oncol Lett 2021 Jun;21(6):475. (PubMed: 33907585)

143). Lin T;Ji Y;Zhao Y;Xia Z; et al. Expression of COX-2 and Nrf2/GPx3 in the anterior vaginal wall tissues of women with pelvic organ prolapse. Arch Gynecol Obstet 2021 Jan 7. (PubMed: 33415437)

144). Wang X;Zeng HC;Huang YR;He QZ; et al. Chlamydia muridarum Alleviates Colitis via the IL-22/Occludin Signal Pathway. Biomed Res Int 2020 Dec 17;2020:8894331. (PubMed: 33381598)

145). Han B;Ge Y;Cui J;Liu B; et al. Down-regulation of lncRNA DNAJC3-AS1 inhibits colon cancer via regulating miR-214-3p/LIVIN axis. Bioengineered 2020 Dec;11(1):524-535. (PubMed: 32352854)

146). Li H et al. Dysifragilone A inhibits LPS‑induced RAW264.7 macrophage activation by blocking the p38 MAPK signaling pathway. Mol Med Rep 2018 Jan;17(1):674-682 (PubMed: 29115475)

147). Han Y et al. Antiangiogenic effects of catalpol on rat corneal neovascularization. Mol Med Rep 2018 Feb;17(2):2187-2194 (PubMed: 29207076)

148). Li H et al. Dysifragilone A inhibits LPS‑induced RAW264.7 macrophage activation by blocking the p38 MAPK signaling pathway. Mol Med Rep 2018 Jan;17(1):674-682 (PubMed: 29115475)

149). Jin X et al. 11-O-acetylcyathatriol inhibits MAPK/p38-mediated inflammation in LPS-activated RAW 264.7 macrophages and has a protective effect on ethanol-induced gastric injury. Mol Med Rep 2016 Jul;14(1):874-80 (PubMed: 27222252)

Application: WB    Species:mouse;    Sample:Not available


150). Luo L et al. Decreased expression of ubiquilin‑1 following neonatal hypoxia‑ischemic brain injury in mice. Mol Med Rep 2019 Apr 15 (PubMed: 31059032)

151). Li WW et al. Synergistic protection of matrine and lycopene against lipopolysaccharide‑induced acute lung injury in mice. Mol Med Rep 2019 Jul;20(1):455-462 (PubMed: 31180535)

152). Zhu Q;Zhang N;Hu N;Jiang R;Lu H;Xuan A;Long D;Chen Y; et al. Neural stem cell transplantation improves learning and memory by protecting cholinergic neurons and restoring synaptic impairment in an amyloid precursor protein/presenilin 1 transgenic mouse model of Alzheimer's disease. Mol Med Rep 2020 Mar;21(3):1172-1180. (PubMed: 31922229)

153). Wu Y;Cui H;Zhang Y;Yu P;Li Y;Wu D;Xue Y;Fu W; et al. Inonotus obliquus extract alleviates myocardial ischemia/reperfusion injury by suppressing endoplasmic reticulum stress. Mol Med Rep 2021 Jan;23(1):77. (PubMed: 33236154)

154). Meng H;Jiang X;Wang J;Sang Z;Guo L;Yin G;Wang Y; et al. SEC61G is upregulated and required for tumor progression in human kidney cancer. Mol Med Rep 2021 Jun;23(6):427. (PubMed: 33846795)

155). Tian H;Chen X;Zhang Y;Wang Y;Fu X;Gu W;Wen Y; et al. Dioscin inhibits SCC15 cell proliferation via the RASSF1A/MST2/YAP axis. Mol Med Rep 2021 Jun;23(6):414. (PubMed: 33786612)

156). Liu X et al. ANNALS EXPRESS: Clinical value of CTLA4-associated microRNAs combined with inflammatory factors in the diagnosis of non-small cell lung cancer. Ann Clin Biochem 2020 Jan 6:4563220901564 (PubMed: 31906699)

157). Dou Y et al. All-trans retinoic acid enhances the effect of Fra-1 to inhibit cell proliferation and metabolism in cervical cancer. Biotechnol Lett 2020 Mar 2 (PubMed: 32124141)

158). Jiang W et al. Identification of Key Candidate Genes and Pathways of Candida albicans-Infected Human Umbilical Vein Endothelial Cells and Drug Screening. Indian J Microbiol 2020 Mar;60(1):62-69 (PubMed: 32089575)

159). Han X et al. The relationship between phospho-p38, MMP-9, and MICA expression in pituitary adenomas demonstrates a new mechanism of pituitary adenoma immune escape. World Neurosurg 2018 Nov 17 (PubMed: 30458325)

160). Han X et al. The Relationship Between Phospho-p38, Matrix Metalloproteinase 9, and Major Histocompatibility Complex Class I Chain-Related Molecule A Expression in Pituitary Adenomas Demonstrates a New Mechanism of Pituitary Adenoma Immune Escape. World Neurosurg 2019 Mar;123:e116-e124 (PubMed: 30458325)

161). Tao M et al. α-Mangostin Alleviated Lipopolysaccharide Induced Acute Lung Injury in Rats by Suppressing NAMPT/NAD Controlled Inflammatory Reactions. Evid Based Complement Alternat Med 2018 Oct 10;2018:5470187 (PubMed: 30405740)

162). Wang Y;Yang Z;Yang L;Zou Q;Zhao S;Hu N;Chen D;Cui R;Ma H; et al. Liuweidihuang Pill Alleviates Inflammation of the Testis via AMPK/SIRT1/NF-κB Pathway in Aging Rats. Evid Based Complement Alternat Med 2020 May 24;2020:2792738. (PubMed: 32565851)

163). Jin X et al. Tiliroside, the major component of Agrimonia pilosa Ledeb ethanol extract, inhibits MAPK/JNK/p38-mediated inflammation in lipopolysaccharide-activated RAW 264.7 macrophages. Exp Ther Med 2016 Jul;12(1):499-505 (PubMed: 27347085)

164). Zhang Q et al. Anti-inflammatory action of ambuic acid, a natural product isolated from the solid culture of Pestalotiopsis neglecta, through blocking ERK/JNK mitogen-activated protein kinase signaling pathway. Exp Ther Med 2018 Aug;16(2):1538-1546 (PubMed: 30116402)

165). Xiaojun Li et al. Recombinant human irisin regulated collagen II, matrix metalloproteinase‑13 and the Wnt/β‑catenin and NF‑κB signaling pathways in interleukin‑1β‑induced human SW1353 cells. EXP THER MED 2020 Feb 26

166). Zhang Y. et al. Effect of iron chelation therapy on EPO-STAT5 signalling pathway and EPO resistance in iron-overloaded low-risk myelodysplastic syndrome patients. Hematology 2020 Dec;25(1):1-10 (PubMed: 31838956)

167). Pan Q et al. A single-stranded DNA aptamer against mannose-capped lipoarabinomannan enhances anti-tuberculosis activity of macrophages through downregulation of lipid-sensing nuclear receptor peroxisome proliferator-activated receptor γ expression. Microbiol Immunol 2017 Feb;61(2):92-102 (PubMed: 28206680)

168). Chen M et al. The Therapeutic Effects and Possible Mechanism of Pranoprofen in Mouse Model of Corneal Alkali Burns. J Ophthalmol 2020 Apr 6;2020:7485912 (PubMed: 32322412)

169). Y. Wu et al. Helium low temperature plasma induced HepG2 cells autophagy through ROS-mediated PI3K/AKT/mTOR/P70s6k signaling pathway. AIP ADV 2019

170). Luo ML et al. Conditioned Medium from Human Umbilical Vein Endothelial Cells Promotes Proliferation, Migration, Invasion and Angiogenesis of Adipose Derived Stem Cells. Curr Med Sci 2018 Feb;38(1):124-130 (PubMed: 30074161)

171). Lin RJ et al. Clinicopathological and prognostic value of NADPH oxidase 2 (NOX2) in primary osteosarcoma. J Orthop Sci 2020 May 10 (PubMed: 32402505)

172). Yuan Q et al. The effect of CA125 on metastasis of ovarian cancer: old marker new function. Oncotarget 2017 Jul 25;8(30):50015-50022 (PubMed: 28637006)

173). Gao H;Sun B;Fu H;Chi X;Wang F;Qi X;Hu J;Shao S; et al. PAK6 promotes cervical cancer progression through activation of the Wnt/β‑catenin signaling pathway. Oncotarget 2016 Aug 16;7(33):53289-53298. (PubMed: 27462866)

174). Xiangli Yan et al. Calycosin-7-O-β-D-glucoside Attenuates OGD/R-Induced Damage by Preventing Oxidative Stress and Neuronal Apoptosis via the SIRT1/FOXO1/PGC-1α Pathway in HT22 Cells. NEURAL PLAST 2019, Article ID 8798069, 11 pages

175). Zhao YX et al. Fine Particulate Matter-Induced Exacerbation of Allergic Asthma via Activation of T-cell Immunoglobulin and Mucin Domain 1. Chin Med J (Engl) 2018 Oct 20;131(20):2461-2473 (PubMed: 30334531)

176). Ma MQ et al. A 6 hour therapeutic window, optimal for interventions targeting AMPK synergism and apoptosis antagonism, for cardioprotection against myocardial ischemic injury: an experimental study on rats. Am J Cardiovasc Dis 2015 Mar 20;5(1):63-71 (PubMed: 26064793)

177). WenjingZong et al. Ginsenoside compound K attenuates cognitive deficits in vascular dementia rats by reducing the Ab deposition. Journal of Pharmacological Sciences 2019

178). et al. Inhibitory effect of 17β‑estradiol on triglyceride synthesis in skeletal muscle cells is dependent on ESR1 and not ESR2.

179). et al. Low dose Bisphenol A (BPA) induced DNA damage and tumorigenic events in MCF-10A cells.

180). et al. Alteration of the Wnt/GSK3β/β‑catenin signalling pathway by rapamycin ameliorates pathology in an Alzheimer's disease model.

181). et al. Evaluation of the age and anatomical areas impact on the properties of canine adipose-derived multipotent mesenchymal stromal cells.

182). et al. Low-dose bisphenol A (BPA)-induced DNA damage and tumorigenic events in MCF-10A cells.

183). et al. Generation and Evaluation of Chicken IgY-scFv for the Purposes of CPV Diagnosis and Therapy.

184). et al. Thermosensitive hydrogels based on methylcellulose derivatives for prevention of postoperative adhesion.

185). Liu Y;Ju M;Wang Z;Li J;Shao C;Fu T;Jing Y;Zhao Y;Lv Z;Li G; et al. The synergistic effect of NELL1 and adipose-derived stem cells on promoting bone formation in osteogenesis imperfecta treatment. Biomed Pharmacother 2020 May 23;128:110235. (PubMed: 32454289)

186). et al. Study on β-Chitosan against the binding of SARS-CoV-2S-RBD/ACE2.

187). et al. The role of long noncoding RNA AL161431. 1 in the development and progression of pancreatic cancer.

188). et al. Effects of 2, 3′, 4, 4′, 5-pentachlorobiphenyl exposure during pregnancy on DNA methylation in the testis of offspring in the mouse.

189). et al. Formononetin Suppresses Interleukin-6 Production in Lipopolysaccharide-Stimulated Macrophages Via Activation of the AMP-Activated Protein Kinase.

190). et al. Antioxidant peptides from Mytilus Coruscus on H2O2-induced human umbilical vein endothelial cell stress.

191). et al. Depletion of Fractalkine Ameliorates Renal Injury and Treg Cell Apoptosis Via the p38MAPK Pathway in Lupus-prone Mice.

192). et al. Effect of soothing liver and invigorating spleen on intestinal permeability and intestinal flora in IBS-D rats.

193). et al. Lipopolysaccharide Affects the Proliferation and Glucose Metabolism of Cervical Cancer Cells Through the FRA1/MDM2/p53 Pathway.

194). et al. Insulin Receptor Substrate p53 Ameliorates High-Glucose-Induced Activation of NF-κB and Impaired Mobility of HUVECs.

195). et al. Structural characterization and immunostimulatory activity in vitro of a glycogen from sea urchin-Strongylocentyotus internedius.

196). et al. MALAT1 sponges miR-26a and miR-26b to regulate endothelial cell angiogenesis via PFKFB3-driven glycolysis in early-onset preeclampsia.

197). Xu N;Luo H;Li M;Wu J;Wu X;Chen L;Gan Y;Guan F;Li M;Su Z;Chen J;Liu Y; et al. β-patchoulene improves lipid metabolism to alleviate non-alcoholic fatty liver disease via activating AMPK signaling pathway. Biomed Pharmacother 2021 Feb;134:111104. (PubMed: 33341045)

198). Liang R;Zhu X;Lan T;Ding D;Zheng Z;Chen T;Huang Y;Liu J;Yang X;Shao J;Wei H;Wei B; et al. TIGIT promotes CD8+ T cells exhaustion and predicts poor prognosis of colorectal cancer. Cancer Immunol Immunother 2021 Feb 26. (PubMed: 33634371)

199). et al. The Neuroprotective Effect of Byu d Mar 25 in LPS-Induced Alzheimer's Disease Mice Model.

200). Sun Y;Lin J;Luo Z;Zhang Y;Chen J; et al. The Serum from Patients with Secondary Frozen Shoulder Following Rotator Cuff Repair Induces Shoulder Capsule Fibrosis and Promotes Macrophage Polarization and Fibroblast Activation. J Inflamm Res 2021 Mar 23;14:1055-1068. (PubMed: 33790620)

201). et al. Resveratrol improves cardiac function and left ventricular fibrosis after myocardial infarction in rats by inhibiting NLRP3 inflammasome activity and the TGF-β1/SMAD2 signaling pathway.

202). Chen Y;Wen J;Chen Z; et al. H2S protects hippocampal neurons against hypoxia-reoxygenation injury by promoting RhoA phosphorylation at Ser188. Cell Death Discov 2021 Jun 4;7(1):132. (PubMed: 34088899)

203). et al. Long non‑coding RNA B3GALT5‑AS1 contributes to the progression of gastric cancer via interacting with CSNK2A1.

204). Shu L;Peng Y;Zhong L;Feng X;Qiao L;Yi Y; et al. CircZNF124 regulates cell proliferation, leucine uptake, migration and invasion by miR‐199b‐5p/SLC7A5 pathway in endometrial cancer. Immun Inflamm Dis 2021 Jun 19. (PubMed: 34145797)

No comment
Total 0 records, divided into1 pages. First Prev Next Last

Submit Review

Support JPG, GIF, PNG format only
captcha
Catalog Number :

S0001-BP
(Blocking peptide available as S0001-BP)

Price/Size :

$350/1mg.
Tips: For phospho antibody, we provide phospho peptide(0.5mg) and non-phospho peptide(0.5mg).

Function :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.

Format and storage :

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.

Precautions :

This product is for research use only. Not for use in diagnostic or therapeutic procedures.

IMPORTANT: For western blots, incubate membrane with diluted secondary antibody in 5% w/v milk , 1X TBS, 0.1% Tween®20 at 37°C, 2H.

To Top