Phospho-HBP1 (Ser402) Antibody - #AF0031
*The optimal dilutions should be determined by the end user.
Cite Format: Affinity Biosciences Cat# AF0031, RRID:AB_2833291.
FLJ16340; HBP 1; HBP1; HBP1_HUMAN; High mobility group box transcription factor 1; HMG box containing protein 1; HMG box transcription factor 1; HMG box-containing protein 1;
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O60381 As Substrate
|S402||Phosphorylation||Q15759 (MAPK11) , Q16539 (MAPK14)||Uniprot|
Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.
Ubiquitinated by the CTLH E3 ubiquitin-protein ligase complex, leading to subsequent proteasomal degradation.
Binds the second PAH repeat of SIN3A (Probable). Binds TCF4. Binds RB1.
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