Musculin Antibody - #AF0343
Product: | Musculin Antibody |
Catalog: | AF0343 |
Description: | Rabbit polyclonal antibody to Musculin |
Application: | WB IHC IF/ICC |
Reactivity: | Human, Rat |
Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
Mol.Wt.: | 22kDa; 22kD(Calculated). |
Uniprot: | O60682 |
RRID: | AB_2833513 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# AF0343, RRID:AB_2833513.
Fold/Unfold
ABF-1; ABF1; Activated B cell factor 1; Activated B-cell factor 1; bHLHa22; Class A basic helix-loop-helix protein 22; Msc; MUSC_HUMAN; Musculin; MYOR;
Immunogens
- O60682 MUSC_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSTGSVSDPEEMELRGLQREYPVPASKRPPLRGVERSYASPSDNSSAEEEDPDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYENGYVHPVNLTWPFVVSGRPDSDTKEVSAANRLCGTTA
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O60682 As Substrate
Site | PTM Type | Enzyme | Source |
---|---|---|---|
Y21 | Phosphorylation | Uniprot | |
K27 | Ubiquitination | Uniprot | |
S45 | Phosphorylation | Uniprot | |
S46 | Phosphorylation | Uniprot |
Research Backgrounds
Transcription repressor capable of inhibiting the transactivation capability of TCF3/E47. May play a role in regulating antigen-dependent B-cell differentiation.
Nucleus.
Expressed in lymphoid tissues, B-cell lines and activated B-cells.
Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a homodimer or a heterodimer. Forms a heterodimer with TCF3.
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For Research Use Only.
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