MVK Antibody | Affinity Biosciences

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Western blot analysis of extracts from 293 cells, using Mevalonate Kinase Antibody.

Product:	MVK Antibody
Catalog:	DF3238
Description:	Rabbit polyclonal antibody to MVK
Application:	WB IHC IF/ICC
Reactivity:	Human, Mouse, Rat
Prediction:	Pig, Bovine, Horse, Sheep, Rabbit, Dog
Mol.Wt.:	42 KD; 42kD(Calculated).
Uniprot:	Q03426
RRID:	AB_2835618

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Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$280	In stock
200ul	$350	In stock

Lead Time: Same day delivery

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Related Downloads

MS Report

HPLC Report

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Rabbit

Application:

WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human,Mouse,Rat

Prediction:

Pig(82%), Bovine(82%), Horse(91%), Sheep(82%), Rabbit(82%), Dog(91%)

Clonality:

Polyclonal

Specificity:

MVK Antibody detects endogenous levels of total MVK.

RRID:

AB_2835618
Cite Format: Affinity Biosciences Cat# DF3238, RRID:AB_2835618.

Conjugate:

Unconjugated.

Purification:

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Storage:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

FLJ96772; KIME_HUMAN; LH receptor mRNA binding protein; LRBP; Mevalonate kinase 1; Mevalonate kinase; Mevalonic aciduria; MK; mvk; MVLK; POROK3;

Immunogens

Immunogen:

Uniprot:

Q03426(KIME_HUMAN) >>Visit HPA database.

Gene(ID):

MVK(4598)

Sequence:

Q03426 KIME_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVPRNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQALTSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species

Results

Score

Horse

Dog

Pig

Bovine

Sheep

Rabbit

Zebrafish

Xenopus

Chicken

Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q03426 As Substrate

Q03426

Site	PTM Type	Source
T37	Phosphorylation	Uniprot
S45	Phosphorylation	Uniprot
K59	Ubiquitination	Uniprot
K90	Ubiquitination	Uniprot
K179	Ubiquitination	Uniprot
K187	Ubiquitination	Uniprot
K220	Ubiquitination	Uniprot
S227	Phosphorylation	Uniprot
K238	Ubiquitination	Uniprot
K330	Ubiquitination	Uniprot
K345	Ubiquitination	Uniprot

Research Backgrounds

Q03426_KIME_HUMAN

Function:

Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis.

Subcellular Location:

Cytoplasm. Peroxisome.

Subunit Structure:

Homodimer.

Family&Domains:

Belongs to the GHMP kinase family. Mevalonate kinase subfamily.

Research Fields

· Cellular Processes > Transport and catabolism > Peroxisome. (View pathway)

· Metabolism > Metabolism of terpenoids and polyketides > Terpenoid backbone biosynthesis.

· Metabolism > Global and overview maps > Metabolic pathways.

Restrictive clause

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.

MVK Antibody - #DF3238