Product: TUFT1 Antibody
Catalog: DF16085
Description: Rabbit polyclonal antibody to TUFT1
Application: WB IF/ICC
Reactivity: Human, Mouse, Rat
Mol.Wt.: 44kD(Calculated).
Uniprot: Q9NNX1

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
TUFT1 Antibody detects endogenous levels of TUFT1.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

MGC188530; TUFT1; TUFT1_HUMAN; Tuftelin 1; Tuftelin;

Immunogens

Immunogen:

A synthesized peptide derived from human TUFT1.

Uniprot:
Gene(ID):
Expression:
Q9NNX1 TUFT1_HUMAN:

Present in the extracellular enamel and is mainly associated with the crystal component.

Sequence:
MNGTRNWCTLVDVHPEDQAAGSVDILRLTLQGELTGDELEHIAQKAGRKTYAMVSSHSAGHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISHGNFSTQARAKTENPGSIRISKPPSPKPMPVIRVVET

Research Backgrounds

Function:

Involved in the mineralization and structural organization of enamel.

Subcellular Location:

Secreted.
Note: Secreted at a very early stage of enamel formation, concentrated at the dentin-enamel junction and tightly bound to the surface of the growing crystallites.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Present in the extracellular enamel and is mainly associated with the crystal component.

Subunit Structure:

Interacts with TFIP11.

Family&Domains:

Belongs to the tuftelin family.

Restrictive clause

 

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