TNNI1 Antibody - #DF15907
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Fold/Unfold
2700018B22Rik; AI747285; DKFZp451O223; si:dz182n13.3; slow skeletal muscle; slow-twitch isoform; SSTNI; TNN1; Tnni1; TNNI1_HUMAN; Troponin I; Troponin I slow skeletal muscle; Troponin I slow twitch isoform; troponin I type 1 (skeletal, slow); Troponin I, slow isoform;
Immunogens
A synthesized peptide derived from human TNNI1.
Highest levels observed in human skeletal muscle (e.g. gastrocnemious muscle), differentiated cultures of primary human muscle cells and rhabdomyosarcoma cells cultured in low serum medium. Expressed in C2 muscle cell myoblasts and myotubes.
- P19237 TNNI1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPEVERKPKITASRKLLLKSLMLAKAKECWEQEHEEREAEKVRYLAERIPTLQTRGLSLSALQDLCRELHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVMDLRGKFKRPPLRRVRVSADAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPVEVGDWRKNVEAMSGMEGRKKMFDAAKSPTSQ
Research Backgrounds
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Highest levels observed in human skeletal muscle (e.g. gastrocnemious muscle), differentiated cultures of primary human muscle cells and rhabdomyosarcoma cells cultured in low serum medium. Expressed in C2 muscle cell myoblasts and myotubes.
Binds to actin and tropomyosin.
Belongs to the troponin I family.
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