PGGT1B Antibody - #DF15151

(2)  
Product: PGGT1B Antibody
Catalog: DF15151
Description: Rabbit polyclonal antibody to PGGT1B
Application: IHC IF/ICC
Reactivity: Human, Mouse, Rat
Mol.Wt.: 42kD(Calculated).
Uniprot: P53609

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
PGGT1B Antibody detects endogenous levels of PGGT1B.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

BGGI; Geranylgeranyl transferase type I subunit beta; Geranylgeranyl transferase type-1 subunit beta; Geranylgeranyltransferase type I beta subunit; GGTase-I-beta; GGTI; PGGT1B; PGTB1_HUMAN; Protein geranylgeranyltransferase type I, beta subunit; Type I protein geranyl-geranyltransferase subunit beta;

Immunogens

Immunogen:

A synthesized peptide derived from human PGGT1B.

Uniprot:

P53609(PGTB1_HUMAN) >>Visit HPA database.

Gene(ID):
PGGT1B(5229)
Sequence:
MAATEDERLAGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLNRCGFRGSSYLGIPFNPSKAPGTAHPYDSGHIAMTYTGLSCLVILGDDLSRVNKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAITYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLLDLHQSWKTKDSKQCSENVHIST

Research Backgrounds

Function:

Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. Known substrates include RAC1, RAC2, RAP1A and RAP1B.

Subunit Structure:

Heterodimer of FNTA and PGGT1B. PGGT1B mediates interaction with substrate peptides.

Family&Domains:

Belongs to the protein prenyltransferase subunit beta family.

Restrictive clause

 

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For Research Use Only.
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