TBKBP1 Antibody - #DF13686
| Product: | TBKBP1 Antibody |
| Catalog: | DF13686 |
| Description: | Rabbit polyclonal antibody to TBKBP1 |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Sheep, Rabbit, Dog, Xenopus |
| Mol.Wt.: | 67kDa; 68kD(Calculated). |
| Uniprot: | A7MCY6 |
| RRID: | AB_2846705 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13686, RRID:AB_2846705.
Fold/Unfold
KIAA0775; ProSAPiP2; SINTBAD; TANK binding kinase 1 binding protein 1; TANK-binding kinase 1-binding protein 1; TBK1 binding protein 1; TBK1-binding protein 1; TBKB1_HUMAN; Tbkbp1;
Immunogens
Detected in leukocytes, lung, placenta, small intestine, liver, kidney, spleen, muscle, heart, brain and at low levels in thymus.
- A7MCY6 TBKB1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MESMFEDDISILTQEALGPSEVWLDSPGDPSLGGDMCSASHFALITAYGDIKERLGGLERENATLRRRLKVYEIKYPLISDFGEEHGFSLYEIKDGSLLEVEKVSLQQRLNQFQHELQKNKEQEEQLGEMIQAYEKLCVEKSDLETELREMRALVETHLRQICGLEQQLRQQQGLQDAAFSNLSPPPAPAPPCTDLDLHYLALRGGSGLSHAGWPGSTPSVSDLERRRLEEALEAAQGEARGAQLREEQLQAECERLQGELKQLQETRAQDLASNQSERDMAWVKRVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPKPRAYGSELYGPGRPLSPRRAFEGIRLRFEKQPSEEDEWAVPTSPPSPEVGTIRCASFCAGFPIPESPAATAYAHAEHAQSWPSINLLMETVGSDIRSCPLCQLGFPVGYPDDALIKHIDSHLENSKI
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - A7MCY6 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S10 | Phosphorylation | Uniprot | |
| T13 | Phosphorylation | Uniprot | |
| Y48 | Phosphorylation | Uniprot | |
| K70 | Ubiquitination | Uniprot | |
| S97 | Phosphorylation | Uniprot | |
| K103 | Ubiquitination | Uniprot | |
| S105 | Phosphorylation | Uniprot | |
| K119 | Ubiquitination | Uniprot | |
| K121 | Ubiquitination | Uniprot | |
| S184 | Phosphorylation | Uniprot | |
| K262 | Ubiquitination | Uniprot | |
| K285 | Ubiquitination | Uniprot | |
| S335 | Phosphorylation | Uniprot | |
| S349 | Phosphorylation | Uniprot | |
| S351 | Phosphorylation | Uniprot | |
| S365 | Phosphorylation | Uniprot | |
| S372 | Phosphorylation | Uniprot | |
| S379 | Phosphorylation | Uniprot | |
| S385 | Phosphorylation | Uniprot | |
| S388 | Phosphorylation | Uniprot | |
| S390 | Phosphorylation | Uniprot | |
| S393 | Phosphorylation | Uniprot | |
| S400 | Phosphorylation | Uniprot | |
| S405 | Phosphorylation | Uniprot | |
| S415 | Phosphorylation | Uniprot | |
| T485 | Phosphorylation | Uniprot | |
| S504 | Phosphorylation | Uniprot | |
| R513 | Methylation | Uniprot | |
| S521 | Phosphorylation | Uniprot | |
| S534 | Phosphorylation | Uniprot |
Research Backgrounds
Adapter protein which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity.
Detected in leukocytes, lung, placenta, small intestine, liver, kidney, spleen, muscle, heart, brain and at low levels in thymus.
Homodimer. May form a heterodimer with NAP1. Interacts with TKB1 and IKBKE.
(Microbial infection) Interacts with vaccinia virus protein C6.
Research Fields
· Organismal Systems > Immune system > RIG-I-like receptor signaling pathway. (View pathway)
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.