USP31 Antibody - #DF9989

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Product: USP31 Antibody
Catalog: DF9989
Description: Rabbit polyclonal antibody to USP31
Application: WB IHC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Sheep, Dog
Mol.Wt.: 147 kDa; 147kD(Calculated).
Uniprot: Q70CQ4
RRID: AB_2843181

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(92%), Bovine(92%), Horse(92%), Sheep(92%), Dog(83%)
Clonality:
Polyclonal
Specificity:
USP31 Antibody detects endogenous levels of total USP31.
RRID:
AB_2843181
Cite Format: Affinity Biosciences Cat# DF9989, RRID:AB_2843181.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Deubiquitinating enzyme 31; KIAA1203; Ubiquitin carboxyl terminal hydrolase 31; Ubiquitin carboxyl-terminal hydrolase 31; Ubiquitin specific peptidase 31; Ubiquitin specific processing protease 31; Ubiquitin specific protease 31; Ubiquitin specific proteinase 31; Ubiquitin thioesterase 31; Ubiquitin thiolesterase 31; Ubiquitin-specific-processing protease 31; UBP31_HUMAN; USP 31; USP31;

Immunogens

Immunogen:
Uniprot:

Q70CQ4(UBP31_HUMAN) >>Visit HPA database.

Gene(ID):
USP31(57478)
Expression:
Q70CQ4 UBP31_HUMAN:

Widely expressed.

Sequence:
MSKVTAPGSGPPAAASGKEKRSFSKRLFRSGRAGGGGAGGPGASGPAAPSSPSSPSSARSVGSFMSRVLKTLSTLSHLSSEGAAPDRGGLRSCFPPGPAAAPTPPPCPPPPASPAPPACAAEPVPGVAGLRNHGNTCFMNATLQCLSNTELFAEYLALGQYRAGRPEPSPDPEQPAGRGAQGQGEVTEQLAHLVRALWTLEYTPQHSRDFKTIVSKNALQYRGNSQHDAQEFLLWLLDRVHEDLNHSVKQSGQPPLKPPSETDMMPEGPSFPVCSTFVQELFQAQYRSSLTCPHCQKQSNTFDPFLCISLPIPLPHTRPLYVTVVYQGKCSHCMRIGVAVPLSGTVARLREAVSMETKIPTDQIVLTEMYYDGFHRSFCDTDDLETVHESDCIFAFETPEIFRPEGILSQRGIHLNNNLNHLKFGLDYHRLSSPTQTAAKQGKMDSPTSRAGSDKIVLLVCNRACTGQQGKRFGLPFVLHLEKTIAWDLLQKEILEKMKYFLRPTVCIQVCPFSLRVVSVVGITYLLPQEEQPLCHPIVERALKSCGPGGTAHVKLVVEWDKETRDFLFVNTEDEYIPDAESVRLQRERHHQPQTCTLSQCFQLYTKEERLAPDDAWRCPHCKQLQQGSITLSLWTLPDVLIIHLKRFRQEGDRRMKLQNMVKFPLTGLDMTPHVVKRSQSSWSLPSHWSPWRRPYGLGRDPEDYIYDLYAVCNHHGTMQGGHYTAYCKNSVDGLWYCFDDSDVQQLSEDEVCTQTAYILFYQRRTAIPSWSANSSVAGSTSSSLCEHWVSRLPGSKPASVTSAASSRRTSLASLSESVEMTGERSEDDGGFSTRPFVRSVQRQSLSSRSSVTSPLAVNENCMRPSWSLSAKLQMRSNSPSRFSGDSPIHSSASTLEKIGEAADDKVSISCFGSLRNLSSSYQEPSDSHSRREHKAVGRAPLAVMEGVFKDESDTRRLNSSVVDTQSKHSAQGDRLPPLSGPFDNNNQIAYVDQSDSVDSSPVKEVKAPSHPGSLAKKPESTTKRSPSSKGTSEPEKSLRKGRPALASQESSLSSTSPSSPLPVKVSLKPSRSRSKADSSSRGSGRHSSPAPAQPKKESSPKSQDSVSSPSPQKQKSASALTYTASSTSAKKASGPATRSPFPPGKSRTSDHSLSREGSRQSLGSDRASATSTSKPNSPRVSQARAGEGRGAGKHVRSSSMASLRSPSTSIKSGLKRDSKSEDKGLSFFKSALRQKETRRSTDLGKTALLSKKAGGSSVKSVCKNTGDDEAERGHQPPASQQPNANTTGKEQLVTKDPASAKHSLLSARKSKSSQLDSGVPSSPGGRQSAEKSSKKLSSSMQTSARPSQKPQ

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
92
Horse
92
Bovine
92
Sheep
92
Dog
83
Chicken
70
Xenopus
0
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q70CQ4 As Substrate

Site PTM Type Enzyme
T5 Phosphorylation
S54 Phosphorylation
S56 Phosphorylation
Y202 Phosphorylation
S343 Phosphorylation
T345 Phosphorylation
T398 Phosphorylation
Y428 Phosphorylation
S433 Phosphorylation
K440 Ubiquitination
T672 Phosphorylation
S684 Phosphorylation
S690 Phosphorylation
Y696 Phosphorylation
S807 Phosphorylation
S814 Phosphorylation
S877 Phosphorylation
S887 Phosphorylation
S914 Phosphorylation
T1022 Phosphorylation
T1023 Phosphorylation
S1028 Phosphorylation
S1029 Phosphorylation
T1032 Phosphorylation
S1052 Phosphorylation
T1056 Phosphorylation
S1057 Phosphorylation
S1060 Phosphorylation
S1089 Phosphorylation
S1100 Phosphorylation
S1103 Phosphorylation
S1106 Phosphorylation
S1109 Phosphorylation
S1111 Phosphorylation
T1122 Phosphorylation
Y1123 Phosphorylation
S1126 Phosphorylation
S1134 Phosphorylation
S1169 Phosphorylation
S1174 Phosphorylation
S1178 Phosphorylation
S1200 Phosphorylation
S1208 Phosphorylation
S1221 Phosphorylation
R1239 Methylation
S1241 Phosphorylation
S1311 Phosphorylation
S1313 Phosphorylation
S1318 Phosphorylation
S1322 Phosphorylation
S1323 Phosphorylation
S1348 Phosphorylation

Research Backgrounds

Function:

May recognize and hydrolyze the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins (By similarity).

Tissue Specificity:

Widely expressed.

Family&Domains:

Belongs to the peptidase C19 family.

References

1). CircARCN1 aggravates atherosclerosis by regulating HuR-mediated USP31 mRNA in macrophages. Cardiovascular research, 2024 (PubMed: 39028686) [IF=10.8]

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