USP24 Antibody - #DF9985

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Product: USP24 Antibody
Catalog: DF9985
Description: Rabbit polyclonal antibody to USP24
Application: WB
Reactivity: Human, Mouse
Prediction: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.: 294 kDa; 294kD(Calculated).
Uniprot: Q9UPU5
RRID: AB_2843177

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(100%), Zebrafish(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(100%)
Clonality:
Polyclonal
Specificity:
USP24 Antibody detects endogenous levels of total USP24.
RRID:
AB_2843177
Cite Format: Affinity Biosciences Cat# DF9985, RRID:AB_2843177.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Deubiquitinating enzyme 24; KIAA1057; Ubiquitin carboxyl terminal hydrolase 24; Ubiquitin carboxyl-terminal hydrolase 24; Ubiquitin specific peptidase 24; Ubiquitin specific processing protease 24; Ubiquitin specific protease 24; Ubiquitin thioesterase 24; Ubiquitin thiolesterase 24; Ubiquitin-specific-processing protease 24; UBP24_HUMAN; Usp24;

Immunogens

Immunogen:
Uniprot:

Q9UPU5(UBP24_HUMAN) >>Visit HPA database.

Gene(ID):
USP24(23358)
Sequence:
MESEEEQHMTTLLCMGFSDPATIRKALRLAKNDINEAVALLTNERPGLDYGGYEPMDSGGGPSPGPGGGPRGDGGGDGGGGGPSRGGSTGGGGGFDPPPAYHEVVDAEKNDENGNCSGEGIEFPTTNLYELESRVLTDHWSIPYKREESLGKCLLASTYLARLGLSESDENCRRFMDRCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLIELVAERIKQDPIPTGLLGVLTMAFNPDNEYHFKNRMKVSQRNWAEVFGEGNMFAVSPVSTFQKEPHGWVVDLVNKFGELGGFAAIQAKLHSEDIELGAVSALIQPLGVCAEYLNSSVVQPMLDPVILTTIQDVRSVEEKDLKDKRLVSIPELLSAVKLLCMRFQPDLVTIVDDLRLDILLRMLKSPHFSAKMNSLKEVTKLIEDSTLSKSVKNAIDTDRLLDWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELTKIWKIQSGQSSTVIENIHTIIAAAAVKFNSDQLNHLFVLIQKSWETESDRVRQKLLSLIGRIGREARFETTSGKVLDVLWELAHLPTLPSSLIQQALEEHLTILSDAYAVKEAIKRSYIIKCIEDIKRPGEWSGLEKNKKDGFKSSQLNNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLVTGSLIACHRLAAAVAGPGGLSGSTLVDGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLESYEITMNGFNLFKTFFENVNLCDHRLKRQGAQLYVEKLELIGMDFIWKIAMESPDEEIANEAIQLIINYSYINLNPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDFYSVPRTILPHGASFHGHLLTLNVTYESTKDTFTVEAHSNETIGSVRWKIAKQLCSPVDNIQIFTNDSLLTVNKDQKLLHQLGFSDEQILTVKTSGSGTPSGSSADSSTSSSSSSSGVFSSSYAMEQEKSLPGVVMALVCNVFDMLYQLANLEEPRITLRVRKLLLLIPTDPAIQEALDQLDSLGRKKTLLSESSSQSSKSPSLSSKQQHQPSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDDMARSCAKSFCENFLKAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQTMPTLLDEDLTKDGIEALSSRPFRNVSRQTSRQMSLCGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEVSDFTSTVACFMRLSWAAAAGRLDLVGSSQPIKESNSLCPAGIRNRLSSSGSNCSSGSEGEPVALHAGICVRQQSVSTKDSLIAGEALSLLVTCLQLRSQQLASFYNLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSAHPDVQKPNQFLLGVILTAQLPLWSPTSIMRGVNQRLLSQCMEYFDLRCQLLDDLTTSEMEQLRISPATMLEDEITWLDNFEPNRTAECETSEADNILLAGHLRLIKTLLSLCGAEKEMLGSSLIKPLLDDFLFRASRIILNSHSPAGSAAISQQDFHPKCSTANSRLAAYEVLVMLADSSPSNLQIIIKELLSMHHQPDPALTKEFDYLPPVDSRSSSGFVGLRNGGATCYMNAVFQQLYMQPGLPESLLSVDDDTDNPDDSVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKMGRDQIFKNTFQGIYSDQKICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRITVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVSGMARQDSSSEVGENGRSVDQGGGGSPRKKVALTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVIEEFDLNDETLEYECFGGEYRPKVYDQTNPYTDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNNDRLSILTKLVKKGEKKGLFVEKMPARIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKLKHPYYPCMAKVSLQLAIQFLFQTYLRTKKKLRVDTEEWIATIEALLSKSFDACQWLVEYFISSEGRELIKIFLLECNVREVRVAVATILEKTLDSALFYQDKLKSLHQLLEVLLALLDKDVPENCKNCAQYFFLFNTFVQKQGIRAGDLLLRHSALRHMISFLLGASRQNNQIRRWSSAQAREFGNLHNTVALLVLHSDVSSQRNVAPGIFKQRPPISIAPSSPLLPLHEEVEALLFMSEGKPYLLEVMFALRELTGSLLALIEMVVYCCFCNEHFSFTMLHFIKNQLETAPPHELKNTFQLLHEILVIEDPIQVERVKFVFETENGLLALMHHSNHVDSSRCYQCVKFLVTLAQKCPAAKEYFKENSHHWSWAVQWLQKKMSEHYWTPQSNVSNETSTGKTFQRTISAQDTLAYATALLNEKEQSGSSNGSESSPANENGDRHLQQGSESPMMIGELRSDLDDVDP

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Xenopus
100
Zebrafish
100
Chicken
100
Rabbit
100
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9UPU5 As Substrate

Site PTM Type Enzyme
K31 Ubiquitination
Y50 Phosphorylation
Y53 Phosphorylation
S58 Phosphorylation
S63 Phosphorylation
S84 Phosphorylation
R85 Methylation
S88 Phosphorylation
K145 Ubiquitination
K152 Ubiquitination
T198 Phosphorylation
Y205 Phosphorylation
S251 Phosphorylation
K287 Ubiquitination
T381 Phosphorylation
K403 Ubiquitination
K421 Ubiquitination
K603 Ubiquitination
K620 Ubiquitination
K648 Ubiquitination
K653 Ubiquitination
K656 Ubiquitination
S657 Phosphorylation
K663 Ubiquitination
K664 Ubiquitination
T673 Phosphorylation
K773 Ubiquitination
Y814 Phosphorylation
K860 Ubiquitination
S881 Phosphorylation
T901 Phosphorylation
S914 Phosphorylation
Y916 Phosphorylation
K1017 Ubiquitination
T1039 Phosphorylation
S1041 Phosphorylation
S1043 Phosphorylation
S1060 Phosphorylation
Y1063 Phosphorylation
K1128 Ubiquitination
S1132 Phosphorylation
S1134 Phosphorylation
S1135 Phosphorylation
S1136 Phosphorylation
S1138 Phosphorylation
S1139 Phosphorylation
K1140 Ubiquitination
S1141 Phosphorylation
S1143 Phosphorylation
T1280 Phosphorylation
S1281 Phosphorylation
S1285 Phosphorylation
T1289 Phosphorylation
K1292 Ubiquitination
S1299 Phosphorylation
S1305 Phosphorylation
T1321 Phosphorylation
S1329 Phosphorylation
T1330 Phosphorylation
K1356 Ubiquitination
S1360 Phosphorylation
S1371 Phosphorylation
S1372 Phosphorylation
S1373 Phosphorylation
S1375 Phosphorylation
S1378 Phosphorylation
S1379 Phosphorylation
S1381 Phosphorylation
T1575 Phosphorylation
S1578 Phosphorylation
S1610 Phosphorylation
S1612 Phosphorylation
S1616 Phosphorylation
S1620 Phosphorylation
K1627 Ubiquitination
K1764 Ubiquitination
S1854 Phosphorylation
Y1857 Phosphorylation
K1899 Ubiquitination
S1935 Phosphorylation
S1943 Phosphorylation
Y2018 Phosphorylation
Y2024 Phosphorylation
T2025 Phosphorylation
S2043 Phosphorylation
S2047 Phosphorylation
S2057 Phosphorylation
S2077 Phosphorylation
S2080 Phosphorylation
S2081 Phosphorylation
K2097 Ubiquitination
K2105 Ubiquitination
Y2117 Phosphorylation
Y2134 Phosphorylation
Y2138 Phosphorylation
Y2157 Phosphorylation
Y2158 Phosphorylation
K2294 Sumoylation
S2307 Phosphorylation
S2330 Phosphorylation
Y2497 Phosphorylation
S2536 Phosphorylation
Y2539 Phosphorylation
T2541 Phosphorylation
K2554 Ubiquitination
T2559 Phosphorylation
S2561 Phosphorylation
T2565 Phosphorylation
Y2568 Phosphorylation
T2570 Phosphorylation
S2587 Phosphorylation
S2588 Phosphorylation
S2602 Phosphorylation
S2604 Phosphorylation
S2613 Phosphorylation

Research Backgrounds

Function:

Ubiquitin-specific protease that regulates cell survival in various contexts through modulating the protein stability of some of its substrates including DDB2, MCL1 or TP53. Plays a positive role on ferritinophagy where ferritin is degraded in lysosomes and releases free iron.

Subunit Structure:

(Microbial infection) Interacts with human cytomegalovirus protein UL38.

Family&Domains:

Belongs to the peptidase C19 family.

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