SFRS16 Antibody - #DF9946

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Product: SFRS16 Antibody
Catalog: DF9946
Description: Rabbit polyclonal antibody to SFRS16
Application: WB IHC
Reactivity: Human, Mouse, Rat
Prediction: Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog
Mol.Wt.: 77 kDa; 77kD(Calculated).
Uniprot: Q8N2M8
RRID: AB_2843140

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Zebrafish(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%)
Clonality:
Polyclonal
Specificity:
SFRS16 Antibody detects endogenous levels of total SFRS16.
RRID:
AB_2843140
Cite Format: Affinity Biosciences Cat# DF9946, RRID:AB_2843140.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

CLASP; CLK4 associating serine/arginine rich protein; Clk4 associating SR related protein; FLJ90109; SFRS16; Splicing factor, arginine/serine rich 16 (suppressor of white apricot homolog, Drosophila); Splicing factor, arginine/serine rich 16; Suppressor of white apricot homolog 2; SWAP2;

Immunogens

Immunogen:
Uniprot:

Q8N2M8(CLASR_HUMAN) >>Visit HPA database.

Gene(ID):
CLASRP(11129)
Sequence:
MWHEARKHERKLRGMMVDYKKRAERRREYYEKIKKDPAQFLQVHGRACKVHLDSAVALAAESPVNMMPWQGDTNNMIDRFDVRAHLDHIPDYTPPLLTTISPEQESDERKCNYERYRGLVQNDFAGISEEQCLYQIYIDELYGGLQRPSEDEKKKLAEKKASIGYTYEDSTVAKVEKAAEKPEEEESAAEEESNSDEDEVIPDIDVEVDVDELNQEQVADLNKQATTYGMADGDFVRMLRKDKEEAEAIKHAKALEEEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRSPHYRH

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
100
Bovine
100
Sheep
100
Dog
100
Zebrafish
100
Rabbit
100
Pig
0
Xenopus
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q8N2M8 As Substrate

Site PTM Type Enzyme
R13 Methylation
S101 Phosphorylation
S106 Phosphorylation
Y228 Phosphorylation
K259 Sumoylation
S263 Phosphorylation
S267 Phosphorylation
S285 Phosphorylation
S288 Phosphorylation
S294 Phosphorylation
T296 Phosphorylation
Y297 Phosphorylation
Y300 Phosphorylation
S305 Phosphorylation
S308 Phosphorylation
S309 Phosphorylation
S317 Phosphorylation
T319 Phosphorylation
T327 Phosphorylation
T330 Phosphorylation
S331 Phosphorylation
S335 Phosphorylation
S379 Phosphorylation
S380 Phosphorylation
S381 Phosphorylation
S382 Phosphorylation
T389 Phosphorylation
S390 Phosphorylation
S391 Phosphorylation
S394 Phosphorylation
S395 Phosphorylation
S417 Phosphorylation
S419 Phosphorylation
S421 Phosphorylation
S423 Phosphorylation
Y432 Phosphorylation
S435 Phosphorylation
S456 Phosphorylation
R460 Methylation
S471 Phosphorylation
S497 Phosphorylation
S499 Phosphorylation
S501 Phosphorylation
S503 Phosphorylation
S505 Phosphorylation
S511 Phosphorylation
S515 Phosphorylation
S521 Phosphorylation
S531 Phosphorylation
S533 Phosphorylation
S535 Phosphorylation
S547 Phosphorylation
K556 Acetylation
K556 Sumoylation
K563 Acetylation
K571 Sumoylation
T573 Phosphorylation
S642 Phosphorylation
S645 Phosphorylation
S647 Phosphorylation
S649 Phosphorylation
Y652 Phosphorylation

Research Backgrounds

Function:

Probably functions as an alternative splicing regulator. May regulate the mRNA splicing of genes such as CLK1. May act by regulating members of the CLK kinase family (By similarity).

PTMs:

Phosphorylated in vitro by CLK4.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Probably interacts with CLK4.

Family&Domains:

Belongs to the splicing factor SR family.

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