SFRS12 Antibody - #DF9945
| Product: | SFRS12 Antibody |
| Catalog: | DF9945 |
| Description: | Rabbit polyclonal antibody to SFRS12 |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Horse, Sheep, Rabbit, Dog, Chicken |
| Mol.Wt.: | 59 kDa; 59kD(Calculated). |
| Uniprot: | Q8WXA9 |
| RRID: | AB_2843139 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9945, RRID:AB_2843139.
Fold/Unfold
DKFZp564B176; MGC133045; Serine-arginine rich splicing regulatory protein 86; Splicing factor, arginine/serine rich 12; Splicing regulatory protein 508; SRrp508; SRrp86;
Immunogens
- Q8WXA9 SREK1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTSLMPGAGLLPIPTPNPLTTLGVSLSSLGAIPAAALDPNIATLGEIPQPPLMGNVDPSKIDEIRRTVYVGNLNSQTTTADQLLEFFKQVGEVKFVRMAGDETQPTRFAFVEFADQNSVPRALAFNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNEENLSTKTEAV
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q8WXA9 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K146 | Ubiquitination | Uniprot | |
| T151 | Phosphorylation | Uniprot | |
| S171 | Phosphorylation | Uniprot | |
| S181 | Phosphorylation | Uniprot | |
| S184 | Phosphorylation | Uniprot | |
| T363 | Phosphorylation | Uniprot | |
| R387 | Methylation | Uniprot | |
| R394 | Methylation | Uniprot | |
| S403 | Phosphorylation | Uniprot | |
| S404 | Phosphorylation | Uniprot | |
| S406 | Phosphorylation | Uniprot | |
| S408 | Phosphorylation | Uniprot | |
| S427 | Phosphorylation | Uniprot | |
| S435 | Phosphorylation | Uniprot | |
| T436 | Phosphorylation | Uniprot | |
| S437 | Phosphorylation | Uniprot | |
| S441 | Phosphorylation | Uniprot | |
| S442 | Phosphorylation | Uniprot |
Research Backgrounds
Participates in the regulation of alternative splicing by modulating the activity of other splice facors. Inhibits the splicing activity of SFRS1, SFRS2 and SFRS6. Augments the splicing activity of SFRS3 (By similarity).
Nucleus.
Homodimer. Binds SFRS1, SFRS2, SFRS3 and SFRS6. Interacts with the spliceosome (By similarity). Interacts with SREK1IP1.
Belongs to the splicing factor SR family.
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For Research Use Only.
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