SLC24A2 Antibody - #DF9940
Product: | SLC24A2 Antibody |
Catalog: | DF9940 |
Description: | Rabbit polyclonal antibody to SLC24A2 |
Application: | WB IHC |
Reactivity: | Human, Mouse, Rat |
Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
Mol.Wt.: | 74 kDa; 74kD(Calculated). |
Uniprot: | Q9UI40 |
RRID: | AB_2843134 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9940, RRID:AB_2843134.
Fold/Unfold
Na(+)/K(+)/Ca(2+) exchange protein 2; Na(+)/K(+)/Ca(2+)-exchange protein 2; NCKX 2; NCKX2_HUMAN; OTTHUMP00000045115; Retinal cone Na Ca+K exchanger; Retinal cone Na-Ca+K exchanger; Slc24a2; Sodium/potassium/calcium exchanger 2; Solute carrier family 24 (sodium/potassium/calcium exchanger) member 2; Solute carrier family 24 member 2;
Immunogens
- Q9UI40 NCKX2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDLQQSTTITSLEKWCLDESLSGCRRHYSVKKKLKLIRVLGLFMGLVAISTVSFSISAFSETDTQSTGEASVVSGPRVAQGYHQRTLLDLNDKILDYTPQPPLSKEGESENSTDHAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREILNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVFMKFNVQVEKWVKQMINRNKVVKVTAPEAQAKPSAARDKDEPTLPAKPRLQRGGSSASLHNSLMRNSIFQLMIHTLDPLAEELGSYGKLKYYDTMTEEGRFREKASILHKIAKKKCHVDENERQNGAANHVEKIELPNSTSTDVEMTPSSDASEPVQNGNLSHNIEGAEAQTADEEEDQPLSLAWPSETRKQVTFLIVFPIVFPLWITLPDVRKPSSRKFFPITFFGSITWIAVFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWLLYTVIHRFQPVAVSSNGLFCAIVLLFIMLLFVILSIALCKWRMNKILGFIMFGLYFVFLVVSVLLEDRILTCPVSI
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9UI40 As Substrate
Site | PTM Type | Enzyme | Source |
---|---|---|---|
N111 | N-Glycosylation | Uniprot | |
S126 | Phosphorylation | Uniprot | |
Y370 | Phosphorylation | Uniprot | |
K391 | Ubiquitination | Uniprot | |
K392 | Ubiquitination | Uniprot | |
K411 | Ubiquitination | Uniprot | |
S647 | Phosphorylation | Uniprot |
Research Backgrounds
Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).
Membrane>Multi-pass membrane protein.
Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
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