SLC9A2 Antibody - #DF9936

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Product: SLC9A2 Antibody
Catalog: DF9936
Description: Rabbit polyclonal antibody to SLC9A2
Application: WB IHC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Rabbit, Dog
Mol.Wt.: 92 kDa; 92kD(Calculated).
Uniprot: Q9UBY0
RRID: AB_2843130

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 100ul $280 In stock
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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Bovine(100%), Horse(92%), Rabbit(92%), Dog(92%)
Clonality:
Polyclonal
Specificity:
SLC9A2 Antibody detects endogenous levels of total SLC9A2.
RRID:
AB_2843130
Cite Format: Affinity Biosciences Cat# DF9936, RRID:AB_2843130.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

H7; Na(+)/H(+) exchanger 2; NHE 2; NHE-2; NHE2; SL9A2_HUMAN; Slc9a2; Sodium/hydrogen exchanger; Sodium/hydrogen exchanger 2; Solute carrier family 9 (sodium/hydrogen exchanger), member 2; Solute carrier family 9 member 2; Solute carrier family 9, member 2;

Immunogens

Immunogen:
Uniprot:

Q9UBY0(SL9A2_HUMAN) >>Visit HPA database.

Gene(ID):
SLC9A2(6549)
Expression:
Q9UBY0 SL9A2_HUMAN:

Expressed in skeletal muscle, colon and kidney. Lower levels in the testis, prostate, ovary, and small intestine.

Sequence:
MEPLGNWRSLRAPLPPMLLLLLLQVAGPVGALAETLLNAPRAMGTSSSPPSPASVVAPGTTLFEESRLPVFTLDYPHVQIPFEITLWILLASLAKIGFHLYHKLPTIVPESCLLIMVGLLLGGIIFGVDEKSPPAMKTDVFFLYLLPPIVLDAGYFMPTRPFFENIGTIFWYAVVGTLWNSIGIGVSLFGICQIEAFGLSDITLLQNLLFGSLISAVDPVAVLAVFENIHVNEQLYILVFGESLLNDAVTVVLYNLFKSFCQMKTIETIDVFAGIANFFVVGIGGVLIGIFLGFIAAFTTRFTHNIRVIEPLFVFLYSYLSYITAEMFHLSGIMAITACAMTMNKYVEENVSQKSYTTIKYFMKMLSSVSETLIFIFMGVSTVGKNHEWNWAFVCFTLAFCLMWRALGVFVLTQVINRFRTIPLTFKDQFIIAYGGLRGAICFALVFLLPAAVFPRKKLFITAAIVVIFFTVFILGITIRPLVEFLDVKRSNKKQQAVSEEIYCRLFDHVKTGIEDVCGHWGHNFWRDKFKKFDDKYLRKLLIRENQPKSSIVSLYKKLEIKHAIEMAETGMISTVPTFASLNDCREEKIRKVTSSETDEIRELLSRNLYQIRQRTLSYNRHSLTADTSERQAKEILIRRRHSLRESIRKDSSLNREHRASTSTSRYLSLPKNTKLPEKLQKRRTISIADGNSSDSDADAGTTVLNLQPRARRFLPEQFSKKSPQSYKMEWKNEVDVDSGRDMPSTPPTPHSREKGTQTSGLLQQPLLSKDQSGSEREDSLTEGIPPKPPPRLVWRASEPGSRKARFGSEKP

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Horse
92
Dog
92
Rabbit
92
Chicken
69
Zebrafish
40
Sheep
0
Xenopus
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9UBY0 As Substrate

Site PTM Type Enzyme
Y356 Phosphorylation
Y361 Phosphorylation
S499 Phosphorylation
Y503 Phosphorylation
K536 Ubiquitination
S551 Phosphorylation
Y610 Phosphorylation
S623 Phosphorylation
S643 Phosphorylation
S647 Phosphorylation
S652 Phosphorylation
S661 Phosphorylation
T662 Phosphorylation
S665 Phosphorylation
Y667 Phosphorylation
S669 Phosphorylation
T674 Phosphorylation
K679 Acetylation
S739 Phosphorylation
S745 Phosphorylation
T746 Phosphorylation
T749 Phosphorylation
S752 Phosphorylation
T757 Phosphorylation

Research Backgrounds

Function:

Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Seems to play an important role in colonic sodium absorption.

PTMs:

Phosphorylated (Possible).

Subcellular Location:

Membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in skeletal muscle, colon and kidney. Lower levels in the testis, prostate, ovary, and small intestine.

Subunit Structure:

Interacts with CHP1 and CHP2.

Family&Domains:

Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

Restrictive clause

 

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