SHOX Antibody - #DF9908
| Product: | SHOX Antibody |
| Catalog: | DF9908 |
| Description: | Rabbit polyclonal antibody to SHOX |
| Application: | WB |
| Reactivity: | Human |
| Prediction: | Dog |
| Mol.Wt.: | 32 kDa; 32kD(Calculated). |
| Uniprot: | O15266 |
| RRID: | AB_2843102 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9908, RRID:AB_2843102.
Fold/Unfold
GCFX; Growth control factor, X linked; Homo sapiens shox gene, alternatively spliced products, complete cds; PHOG; Pseudoautosomal homeobox containing osteogenic; Pseudoautosomal homeobox containing osteogenic protein; Pseudoautosomal homeobox-containing osteogenic protein; Short stature homeobox; Short stature homeobox containing protein; Short stature homeobox protein; Short stature homeobox-containing protein; SHOX; SHOX_HUMAN; SHOXY; SS; Turner syndrome;
Immunogens
SHOXA is expressed in skeletal muscle, placenta, pancreas, heart and bone marrow fibroblast and SHOXB is highly expressed in bone marrow fibroblast followed by kidney and skeletal muscle. SHOXB is not expressed in brain, kidney, liver and lung. Highly expressed in osteogenic cells.
- O15266 SHOX_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEELTAFVSKSFDQKSKDGNGGGGGGGGKKDSITYREVLESGLARSRELGTSDSSLQDITEGGGHCPVHLFKDHVDNDKEKLKEFGTARVAEGIYECKEKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTANHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O15266 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T5 | Phosphorylation | Uniprot | |
| S9 | Phosphorylation | Uniprot | |
| K17 | Ubiquitination | Uniprot | |
| K29 | Sumoylation | Uniprot | |
| K30 | Acetylation | Uniprot | |
| S46 | Phosphorylation | Uniprot | |
| S106 | Phosphorylation | P68400 (CSNK2A1) | Uniprot |
| S120 | Phosphorylation | Uniprot | |
| T125 | Phosphorylation | Uniprot | |
| Y141 | Phosphorylation | Uniprot |
Research Backgrounds
Controls fundamental aspects of growth and development.
Nucleus.
SHOXA is expressed in skeletal muscle, placenta, pancreas, heart and bone marrow fibroblast and SHOXB is highly expressed in bone marrow fibroblast followed by kidney and skeletal muscle. SHOXB is not expressed in brain, kidney, liver and lung. Highly expressed in osteogenic cells.
Belongs to the paired homeobox family. Bicoid subfamily.
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