SH3BGRL3 Antibody - #DF9905

(1)   (3)  
Product: SH3BGRL3 Antibody
Catalog: DF9905
Description: Rabbit polyclonal antibody to SH3BGRL3
Application: WB IHC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Rabbit, Dog, Chicken
Mol.Wt.: 10 kDa; 10kD(Calculated).
Uniprot: Q9H299
RRID: AB_2843099

View similar products>>

   Size Price Inventory
 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

For pricing and ordering contact:
Local distributors
Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Rabbit(100%), Dog(100%), Chicken(92%)
Clonality:
Polyclonal
Specificity:
SH3BGRL3 Antibody detects endogenous levels of total SH3BGRL3.
RRID:
AB_2843099
Cite Format: Affinity Biosciences Cat# DF9905, RRID:AB_2843099.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

epididymis secretory protein Li 297; HEL-S-297; SH3 domain binding glutamic acid rich protein like 3; SH3 domain-binding glutamic acid-rich-like protein 3; SH3 domain-binding protein 1; Sh3bgrl3; SH3BGRL3 like protein; SH3BP-1; SH3L3_HUMAN; TIP B1; TIP-B1; TNF inhibitory protein;

Immunogens

Immunogen:
Uniprot:

Q9H299(SH3L3_HUMAN) >>Visit HPA database.

Gene(ID):
SH3BGRL3(83442)
Expression:
Q9H299 SH3L3_HUMAN:

Ubiquitous.

Sequence:
MSGLRVYSTSVTGSREIKSQQSEVTRILDGKRIQYQLVDISQDNALRDEMRALAGNPKATPPQIVNGDQYCGDYELFVEAVEQNTLQEFLKLA

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Dog
100
Rabbit
100
Chicken
92
Zebrafish
69
Xenopus
62
Sheep
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9H299 As Substrate

Site PTM Type Enzyme
S2 Acetylation
R5 Methylation
Y7 Phosphorylation
K18 Acetylation
K18 Ubiquitination
Y35 Phosphorylation
R47 Methylation
K58 Ubiquitination
T60 Phosphorylation
Y70 Phosphorylation
Y74 Phosphorylation

Research Backgrounds

Function:

Could act as a modulator of glutaredoxin biological activity.

Subcellular Location:

Cytoplasm. Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Ubiquitous.

Family&Domains:

Belongs to the SH3BGR family.

References

1). Differential expression of serum proteins before 20 weeks gestation in women with hypertensive disorders of pregnancy: A potential role for SH3BGRL3. Placenta, 2021 (PubMed: 33217630) [IF=3.8]

Application: IF/ICC    Species: Human    Sample: placenta tissue

Fig. 2. Median serum levels of (A) endoglin and (B) SH3BGRL3 before 20 weeks gestation in women who experienced an uncomplicated pregnancy and women who later developed HDP by quantitative proteomics (***P < 0.001). C: Confocal microscope images of anti-SH3BGRL3 in placenta tissue. The immunoreactivity of SH3BGRL3 (red) was higher in HDP patients compared to normal pregnancies. Cell nuclei were stained with DAPI (blue). Original magnification 40 × .

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.