STAC3 Antibody - #DF9900
| Product: | STAC3 Antibody |
| Catalog: | DF9900 |
| Description: | Rabbit polyclonal antibody to STAC3 |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 42 kDa; 42kD(Calculated). |
| Uniprot: | Q96MF2 |
| RRID: | AB_2843094 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9900, RRID:AB_2843094.
Fold/Unfold
MGC2793; SH3 and cysteine rich domain 3; SH3 and cysteine rich domain-containing protein 3; SH3 and cysteine-rich domain-containing protein 3; stac3; STAC3_HUMAN;
Immunogens
- Q96MF2 STAC3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTEKEVLESPKPSFPAETRQSGLQRLKQLLRKGSTGTKEMELPPEPQANGEAVGAGGGPIYYIYEEEEEEEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKDLSAANRNDPVFETLRTGVIMANKERKKGQADKKNPVAAMMEEEPESARPEEGKPQDGNPEGDKKAEKKTPDDKHKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDFLEEI
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q96MF2 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S34 | Phosphorylation | Uniprot | |
| T37 | Phosphorylation | Uniprot | |
| T183 | Phosphorylation | Uniprot |
Research Backgrounds
Required for normal excitation-contraction coupling in skeletal muscle and for normal muscle contraction in response to membrane depolarization. Required for normal Ca(2+) release from the sarcplasmic reticulum, which ultimately leads to muscle contraction. Probably functions via its effects on muscle calcium channels. Increases CACNA1S channel activity, in addition to its role in enhancing the expression of CACNA1S at the cell membrane. Has a redundant role in promoting the expression of the calcium channel CACNA1S at the cell membrane (By similarity). Slows down the inactivation rate of the calcium channel CACNA1C.
Cytoplasm. Cell membrane>Sarcolemma>Peripheral membrane protein>Cytoplasmic side. Cell membrane>Sarcolemma>T-tubule.
Note: Co-localizes with CACNA1S and CACNA1C on T-tubules.
Interacts (via SH3 domains) with the calcium channels CACNA1S and CACNA1C. Component of a calcium channel complex with CACNA1S and CACNB1. Component of a calcium channel complex with CACNA1C and CACNB1 (By similarity).
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