SH2D4A Antibody - #DF9897
| Product: | SH2D4A Antibody |
| Catalog: | DF9897 |
| Description: | Rabbit polyclonal antibody to SH2D4A |
| Application: | WB IHC |
| Reactivity: | Human |
| Prediction: | Dog |
| Mol.Wt.: | 53 kDa; 53kD(Calculated). |
| Uniprot: | Q9H788 |
| RRID: | AB_2843091 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9897, RRID:AB_2843091.
Fold/Unfold
FLJ20967; PPP1R38; Protein phosphatase 1 regulatory subunit 38; Protein SH; Protein SH(2)A; Protein SH2A; SH2 domain containing 4A; SH2 domain containing protein 4A; SH2 domain-containing protein 4A; SH24A_HUMAN; SH2A; Sh2d4a;
Immunogens
- Q9H788 SH24A_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLKQILSEMYIDPDLLAELSEEQKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKKENGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEEFTNSLKTKSQYHDLQAPDNQQTKDIWKKVAEKEELEQGSRPAPTLEEEKIRSLSSSSRNIQQMLADSINRMKAYAFHQKKESMKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSKAADEKRRSLAKQAREDYKRLSLGAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAYPQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANELLLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLVEYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9H788 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y10 | Phosphorylation | Uniprot | |
| K49 | Ubiquitination | Uniprot | |
| S51 | Phosphorylation | Uniprot | |
| K55 | Ubiquitination | Uniprot | |
| K69 | Acetylation | Uniprot | |
| K69 | Ubiquitination | Uniprot | |
| K105 | Sumoylation | Uniprot | |
| K105 | Ubiquitination | Uniprot | |
| K115 | Ubiquitination | Uniprot | |
| S118 | Phosphorylation | Uniprot | |
| S124 | Phosphorylation | Uniprot | |
| K126 | Ubiquitination | Uniprot | |
| K128 | Methylation | Uniprot | |
| K128 | Ubiquitination | Uniprot | |
| S129 | Phosphorylation | Uniprot | |
| Y131 | Phosphorylation | Uniprot | |
| K143 | Ubiquitination | Uniprot | |
| K152 | Ubiquitination | Uniprot | |
| K169 | Ubiquitination | Uniprot | |
| S177 | Phosphorylation | Uniprot | |
| S187 | Phosphorylation | Uniprot | |
| K199 | Ubiquitination | Uniprot | |
| S235 | Phosphorylation | Uniprot | |
| K240 | Methylation | Uniprot | |
| S261 | Phosphorylation | Q96GD4 (AURKB) | Uniprot |
| S275 | Phosphorylation | Uniprot | |
| K303 | Acetylation | Uniprot | |
| T313 | Phosphorylation | Uniprot | |
| S315 | Phosphorylation | Uniprot | |
| S316 | Phosphorylation | Uniprot | |
| S317 | Phosphorylation | Uniprot | |
| K327 | Sumoylation | Uniprot | |
| K327 | Ubiquitination | Uniprot |
Research Backgrounds
Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.
Cytoplasm.
Note: Located at podocyte foot processes.
Ubiquitously expressed. Aberrantly expressed in some cancers.
Interacts with ESR1.
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