Product: RND2 Antibody
Catalog: DF9867
Description: Rabbit polyclonal antibody to RND2
Application: WB IHC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog
Mol.Wt.: 25 kDa; 25kD(Calculated).
Uniprot: P52198
RRID: AB_2843061

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(92%), Bovine(92%), Horse(92%), Sheep(92%), Rabbit(92%), Dog(92%)
Clonality:
Polyclonal
Specificity:
RND2 Antibody detects endogenous levels of total RND2.
RRID:
AB_2843061
Cite Format: Affinity Biosciences Cat# DF9867, RRID:AB_2843061.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

ARHN; CTD-3199J23.4; GTP-binding protein Rho7; ras homolog gene family, member N; Rho 7; Rho family GTPase 2; Rho N; Rho related GTP-binding protein RhoN; Rho-related GTP-binding protein Rho7; Rho-related GTP-binding protein RhoN; Rho7; RhoN; Rnd 2; Rnd2; RND2_HUMAN;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
P52198 RND2_HUMAN:

Highly expressed in testis.

Sequence:
MEGQSGRCKIVVVGDAECGKTALLQVFAKDAYPGSYVPTVFENYTASFEIDKRRIELNMWDTSGSSYYDNVRPLAYPDSDAVLICFDISRPETLDSVLKKWQGETQEFCPNAKVVLVGCKLDMRTDLATLRELSKQRLIPVTHEQGTVLAKQVGAVSYVECSSRSSERSVRDVFHVATVASLGRGHRQLRRTDSRRGMQRSAQLSGRPDRGNEGEIHKDRAKSCNLM

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
92
Horse
92
Bovine
92
Sheep
92
Dog
92
Rabbit
92
Zebrafish
50
Xenopus
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P52198 As Substrate

Site PTM Type Enzyme
R184 Methylation
S205 Phosphorylation

Research Backgrounds

Function:

May be specifically involved in neuronal and hepatic functions. Is a C3 toxin-insensitive member of the Rho subfamily (By similarity).

Subcellular Location:

Cytoplasmic vesicle>Secretory vesicle>Acrosome membrane>Lipid-anchor>Cytoplasmic side.
Note: Colocalizes with RACGAP1 in Golgi-derived proacrosomal vesicles and the acrosome.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Highly expressed in testis.

Subunit Structure:

Interacts with the Rho-GAP domain of RACGAP1. Interacts with UBXD5. Interacts with PRAG1 (By similarity).

Family&Domains:

Belongs to the small GTPase superfamily. Rho family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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