RHG6 Antibody - #DF9863
(4)
| Product: | RHG6 Antibody |
| Catalog: | DF9863 |
| Description: | Rabbit polyclonal antibody to RHG6 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Mol.Wt.: | 106 kDa; 106kD(Calculated). |
| Uniprot: | O43182 |
| RRID: | AB_2843057 |
Product Info
Source:
Rabbit
Application:
IF/ICC 1:100-1:500, IHC 1:50-1:200, WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
RHG6 Antibody detects endogenous levels of total RHG6.
RRID:
AB_2843057
Cite Format: Affinity Biosciences Cat# DF9863, RRID:AB_2843057.
Cite Format: Affinity Biosciences Cat# DF9863, RRID:AB_2843057.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Immunogens
Immunogen:
Uniprot:
Gene(ID):
Expression:
O43182 RHG06_HUMAN:
Highly expressed in kidney, heart and skeletal muscle followed by retina, lymphoblast, placenta, lung, brain, pancreas and liver.
Sequence:
- O43182 RHG06_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSAQSLLHSVFSCSSPASSSAASAKGFSKRKLRQTRSLDPALIGGCGSDEAGAEGSARGATAGRLYSPSLPAESLGPRLASSSRGPPPRATRLPPPGPLCSSFSTPSTPQEKSPSGSFHFDYEVPLGRGGLKKSMAWDLPSVLAGPASSRSASSILCSSGGGPNGIFASPRRWLQQRKFQSPPDSRGHPYVVWKSEGDFTWNSMSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCDLSCQITIPKDGQKRKKSLRKKLDSLGKEKNKDKEFIPQAFGMPLSQVIANDRAYKLKQDLQRDEQKDASDFVASLLPFGNKRQNKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRGAMSVDSITDLDDNQSRLLEALQLSLPAEAQSKKEKARDKKLSLNPIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGIDVSLEEEHSVHDVAALLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDMLQSEVSFSVGGRHSSTDSNKASSGDISPYDNNSPVLSERSLLAMQEDAAPGGSEKLYRVPGQFMLVGHLSSSKSRESSPGPRLGKDLSEEPFDIWGTWHSTLKSGSKDPGMTGSSGDIFESSSLRAGPCSLSQGNLSPNWPRWQGSPAELDSDTQGARRTQAAAPATEGRAHPAVSRACSTPHVQVAGKAERPTARSEQYLTLSGAHDLSESELDVAGLQSRATPQCQRPHGSGRDDKRPPPPYPGPGKPAAAAAWIQGPPEGVETPTDQGGQAAEREQQVTQKKLSSANSLPAGEQDSPRLGDAGWLDWQRERWQIWELLSTDNPDALPETLV
PTMs - O43182 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S37 | Phosphorylation | Uniprot | |
| S69 | Phosphorylation | Uniprot | |
| S74 | Phosphorylation | Uniprot | |
| R84 | Methylation | Uniprot | |
| R128 | Methylation | Uniprot | |
| S141 | Phosphorylation | Uniprot | |
| K260 | Acetylation | Uniprot | |
| S264 | Phosphorylation | Uniprot | |
| K267 | Acetylation | Uniprot | |
| K269 | Acetylation | Uniprot | |
| T349 | Phosphorylation | Uniprot | |
| S363 | Phosphorylation | Uniprot | |
| S366 | Phosphorylation | Uniprot | |
| S384 | Phosphorylation | Uniprot | |
| S402 | Phosphorylation | Uniprot | |
| Y407 | Phosphorylation | Uniprot | |
| S633 | Phosphorylation | Uniprot | |
| S637 | Phosphorylation | Uniprot | |
| S663 | Phosphorylation | Uniprot | |
| S667 | Phosphorylation | Uniprot | |
| S673 | Phosphorylation | Uniprot | |
| S680 | Phosphorylation | Uniprot | |
| S711 | Phosphorylation | Uniprot | |
| S744 | Phosphorylation | Uniprot | |
| S754 | Phosphorylation | Uniprot | |
| S772 | Phosphorylation | Uniprot | |
| S777 | Phosphorylation | Uniprot | |
| S786 | Phosphorylation | Uniprot | |
| S820 | Phosphorylation | Uniprot | |
| S850 | Phosphorylation | Uniprot | |
| S928 | Phosphorylation | Uniprot | |
| S931 | Phosphorylation | Uniprot | |
| S939 | Phosphorylation | Uniprot |
Research Backgrounds
Function:
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Could regulate the interactions of signaling molecules with the actin cytoskeleton. Promotes continuous elongation of cytoplasmic processes during cell motility and simultaneous retraction of the cell body changing the cell morphology.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Highly expressed in kidney, heart and skeletal muscle followed by retina, lymphoblast, placenta, lung, brain, pancreas and liver.
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