RHG4 Antibody - #DF9862
| Product: | RHG4 Antibody |
| Catalog: | DF9862 |
| Description: | Rabbit polyclonal antibody to RHG4 |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Bovine, Horse |
| Mol.Wt.: | 105 kDa; 105kD(Calculated). |
| Uniprot: | P98171 |
| RRID: | AB_2843056 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9862, RRID:AB_2843056.
Fold/Unfold
ARHGAP 4; C1; GTPase-activating protein, Rho, 4; KIAA0131; OTTHUMP00000026004; p115; RGC 1; RGC1; Rho GAP hematopoietic protein C1; Rho GAP hematopoietic protein C1; Rho GTPase activating protein 4; Rho type GTPase activating protein 4; RhoGAP 4; RhoGAP4; SrGAP4;
Immunogens
Predominantly in hematopoietic cells (spleen, thymus and leukocytes); low levels in placenta, lung and various fetal tissues.
- P98171 RHG04_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAHGKLRRERGLQAEYETQVKEMRWQLSEQLRCLELQGELRRELLQELAEFMRRRAEVELEYSRGLEKLAERFSSRGGRLGSSREHQSFRKEPSLLSPLHCWAVLLQHTRQQSRESAALSEVLAGPLAQRLSHIAEDVGRLVKKSRDLEQQLQDELLEVVSELQTAKKTYQAYHMESVNAEAKLREAERQEEKRAGRSVPTTTAGATEAGPLRKSSLKKGGRLVEKRQAKFMEHKLKCTKARNEYLLSLASVNAAVSNYYLHDVLDLMDCCDTGFHLALGQVLRSYTAAESRTQASQVQGLGSLEEAVEALDPPGDKAKVLEVHATVFCPPLRFDYHPHDGDEVAEICVEMELRDEILPRAQNIQSRLDRQTIETEEVNKTLKATLQALLEVVASDDGDVLDSFQTSPSTESLKSTSSDPGSRQAGRRRGQQQETETFYLTKLQEYLSGRSILAKLQAKHEKLQEALQRGDKEEQEVSWTQYTQRKFQKSRQPRPSSQYNQRLFGGDMEKFIQSSGQPVPLVVESCIRFINLNGLQHEGIFRVSGAQLRVSEIRDAFERGEDPLVEGCTAHDLDSVAGVLKLYFRSLEPPLFPPDLFGELLASSELEATAERVEHVSRLLWRLPAPVLVVLRYLFTFLNHLAQYSDENMMDPYNLAVCFGPTLLPVPAGQDPVALQGRVNQLVQTLIVQPDRVFPPLTSLPGPVYEKCMAPPSASCLGDAQLESLGADNEPELEAEMPAQEDDLEGVVEAVACFAYTGRTAQELSFRRGDVLRLHERASSDWWRGEHNGMRGLIPHKYITLPAGTEKQVVGAGLQTAGESGSSPEGLLASELVHRPEPCTSPEAMGPSGHRRRCLVPASPEQHVEVDKAVAQNMDSVFKELLGKTSVRQGLGPASTTSPSPGPRSPKAPPSSRLGRNKGFSRGPGAPASPSASHPQGLDTTPKPH
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P98171 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y17 | Phosphorylation | Uniprot | |
| K22 | Ubiquitination | Uniprot | |
| K69 | Ubiquitination | Uniprot | |
| S83 | Phosphorylation | Uniprot | |
| S89 | Phosphorylation | Uniprot | |
| K92 | Ubiquitination | Uniprot | |
| K168 | Ubiquitination | Uniprot | |
| K169 | Ubiquitination | Uniprot | |
| Y171 | Phosphorylation | Uniprot | |
| K184 | Ubiquitination | Uniprot | |
| S199 | Phosphorylation | Uniprot | |
| T202 | Phosphorylation | Uniprot | |
| T204 | Phosphorylation | Uniprot | |
| S217 | Phosphorylation | Uniprot | |
| K236 | Ubiquitination | Uniprot | |
| K318 | Ubiquitination | Uniprot | |
| K320 | Ubiquitination | Uniprot | |
| T376 | Phosphorylation | Uniprot | |
| K381 | Ubiquitination | Uniprot | |
| K384 | Ubiquitination | Uniprot | |
| S408 | Phosphorylation | Uniprot | |
| S410 | Phosphorylation | Uniprot | |
| S419 | Phosphorylation | Uniprot | |
| K443 | Ubiquitination | Uniprot | |
| K456 | Ubiquitination | Uniprot | |
| K463 | Ubiquitination | Uniprot | |
| K473 | Ubiquitination | Uniprot | |
| S479 | Phosphorylation | Uniprot | |
| Y483 | Phosphorylation | Uniprot | |
| S497 | Phosphorylation | Uniprot | |
| S498 | Phosphorylation | Uniprot | |
| K511 | Ubiquitination | Uniprot | |
| Y584 | Phosphorylation | Uniprot | |
| S587 | Phosphorylation | Uniprot | |
| Y706 | Phosphorylation | Uniprot | |
| K798 | Ubiquitination | Uniprot | |
| S824 | Phosphorylation | Uniprot | |
| S842 | Phosphorylation | Uniprot | |
| S860 | Phosphorylation | Uniprot | |
| S887 | Phosphorylation | Uniprot | |
| S899 | Phosphorylation | Uniprot | |
| S901 | Phosphorylation | Uniprot | |
| S906 | Phosphorylation | Uniprot | |
| S922 | Phosphorylation | Uniprot | |
| S930 | Phosphorylation | Uniprot | |
| S932 | Phosphorylation | Uniprot | |
| S934 | Phosphorylation | Uniprot | |
| T941 | Phosphorylation | Uniprot | |
| T942 | Phosphorylation | Uniprot |
Research Backgrounds
Inhibitory effect on stress fiber organization. May down-regulate Rho-like GTPase in hematopoietic cells.
Cytoplasm.
Note: Just below the plasma membrane.
Predominantly in hematopoietic cells (spleen, thymus and leukocytes); low levels in placenta, lung and various fetal tissues.
Interacts with NCKAP1L.
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