RAB6B Antibody - #DF9835
| Product: | RAB6B Antibody |
| Catalog: | DF9835 |
| Description: | Rabbit polyclonal antibody to RAB6B |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus |
| Mol.Wt.: | 23 kDa; 23kD(Calculated). |
| Uniprot: | Q9NRW1 |
| RRID: | AB_2843029 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9835, RRID:AB_2843029.
Fold/Unfold
9630015C03; AI844641; C330006L04Rik; D9Bwg0185e; OTTHUMP00000216372; RAB6B; RAB6B member RAS oncogene family; RAB6B_HUMAN; Ras related protein Rab 6B; Ras-related protein Rab-6B; Small GTP binding protein; Small GTPase RAB6B;
Immunogens
- Q9NRW1 RAB6B_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSAGGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVIIMLVGNKTDLADKRQITIEEGEQRAKELSVMFIETSAKTGYNVKQLFRRVASALPGMENVQEKSKEGMIDIKLDKPQEPPASEGGCSC
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NRW1 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Phosphorylation | Uniprot | |
| S23 | Phosphorylation | Uniprot | |
| K26 | Ubiquitination | Uniprot | |
| Y35 | Phosphorylation | Uniprot | |
| S37 | Phosphorylation | Uniprot | |
| S52 | Phosphorylation | Uniprot | |
| T54 | Phosphorylation | Uniprot | |
| Y56 | Phosphorylation | Uniprot | |
| R60 | Methylation | Uniprot | |
| T61 | Phosphorylation | Uniprot | |
| T69 | Phosphorylation | Uniprot | |
| S77 | Phosphorylation | Uniprot | |
| R112 | Methylation | Uniprot | |
| K127 | Ubiquitination | Uniprot | |
| T137 | Phosphorylation | Uniprot | |
| S172 | Phosphorylation | Uniprot |
Research Backgrounds
Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells.
Golgi apparatus membrane>Lipid-anchor. Endoplasmic reticulum-Golgi intermediate compartment. Cytoplasmic vesicle.
Note: Colocalizes with BICD1 at vesicular structures that align along microtubules.
Predominantly expressed in brain.
Interacts with BICDL1/BICDR1; leads to its accumulation in the pericentrosomal region (By similarity). Interacts with RAB6KIFL. Interacts (GTP-bound) with BICD1 (via C-terminus); the interaction is direct. Interacts (GDP-bound) with DYNLRB1. Interacts (GTP-bound) with APBA1/MINT1 isoform 2, also called Mint1_826, but not with isoform 1.
Belongs to the small GTPase superfamily. Rab family.
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